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Approved by the FDA in 2005 as the first drug with a race-specific indication on its label, BiDil was touted as a pathbreaking therapy to treat heart failure in black patients. Kahn reveals that, at the most basic level, BiDil became racial through legal maneuvering and commercial pressure as much as through medical understandings of how the drug worked. He examines the legal and calls for a more reasoned approach to using race in biomedical research and practice.
In 2000, with the success of the Human Genome Project, scientists declared the death of race in biology and medicine. But within five years, many of these same scientists had reversed course and embarked upon a new hunt for the biological meaning of race. Drawing on personal interviews and life stories, Race Decoded takes us into the world of elite genome scientists—including Francis Collins, director of the NIH; Craig Venter, the first person to create a synthetic genome; and Spencer Wells, National Geographic Society explorer-in-residence, among others—to show how and why they are formulating new ways of thinking about race. In this original exploration, Catherine Bliss reveals a parad...
If you understand heart failure, you understand cardiology This book applies practical clinical concepts to the latest four-stage model of heart failure from preclinical risk and early asymptomatic disease to classic symptomatic heart failure and finally advanced heart failure. This framework emphasizes a tailored approach to ongoing heart failure assessment to guide therapy and improve outcomes. Features: Illustrated with over 250 full-color figuresSpecific recommendations backed by clinical trial dataPractical algorithms for diagnosis and therapy Topics include: Prevention of heart failureIdentification and treatment of structural heart disease prior to heart failureHow to combine lifestyl...
Although the majority of heart failure represents the exacerbation of chronic disease, about 20% will present as a first time diagnosis. And although there are a number of intravenous agents that can be used for acute decompensated heart failure, there are no national guidelines currently available. Edited by a well-known expert and his team of con
"The most up-to-date, definitive reference book about statins, this is a cross-examination of the claims about the safety of this controversial drug, by the director of the Women's Cardiac Center at The Miriam Hospital in Providence, RI"--
There is growing recognition that the United States' clinical trials enterprise (CTE) faces great challenges. There is a gap between what is desired - where medical care is provided solely based on high quality evidence - and the reality - where there is limited capacity to generate timely and practical evidence for drug development and to support medical treatment decisions. With the need for transforming the CTE in the U.S. becoming more pressing, the IOM Forum on Drug Discovery, Development, and Translation held a two-day workshop in November 2011, bringing together leaders in research and health care. The workshop focused on how to transform the CTE and discussed a vision to make the enterprise more efficient, effective, and fully integrated into the health care system. Key issue areas addressed at the workshop included: the development of a robust clinical trials workforce, the alignment of cultural and financial incentives for clinical trials, and the creation of a sustainable infrastructure to support a transformed CTE. This document summarizes the workshop.
This book offers research geared toward understanding culture and its influence on the success of global businesses. Divided into two parts that look at the leveraging culture cultural diversity from an organizational as well as national perspective, the chapters investigate the effects of technology on culture, the role of leadership in corporate culture, and communicating and managing change across cultures. The book emphasizes that embracing cultural and subcultural differences alongside instilling organizational culture are the keys to successful modern business. With contributions from authors from academic as well as professional backgrounds, this book will serve as a valuable resource to researchers interested in cultural studies generally as well as those studying the importance of culture to managing modern organizations.
Medical errors are one of the leading causes of death. Deliver the highest quality care to your patients by recognizing and minimizing common mistakes. Providing quality care free of clinical errors isn't just a matter of knowing what to do in any given situation—it's about actively knowing what not to do. Mistake-Based Learning in Cardiology: Avoiding Medical Errors provides healthcare professionals with a summary of the common ways to inadvertently cause medical errors for each major clinical action. This resource also provides valuable information on why the mistake may be made and openly discusses medical errors to facilitate growth, learning, and psychological safety in today's workpl...
This handbook covers the history of philosophy of biology then moves on to evolutionary theory. It continues with discussions of molecular biology and ecology, and covers biology and ethics as well as biology and religion.
This issue of Heart Failure Clinics, devoted to Interventional and Device Therapy in Heart Failure, is edited by Deepak L. Bhatt and Michael R. Gold. Topics include The Role of Implantable Hemodynamic Monitors to Manage Heart Failure; Non-hemodynamic Parameters from Implantable Devices for Heart Failure Risk Stratification; Role of Percutaneous Revascularization in Patients to Improve Left Ventricular Function; Hemodynamic Support with Percutaneous Devices in Patients with Heart Failure; Transcatheter Aortic Valve Replacement for Patients with Heart Failure; Percutaneous Intervention for Mitral Regurgitation; Percutaneous Left Ventricular Remodeling; Stem Cell Therapy for Heart Failure; Implantable Cardioverter Defibrillator Therapy; Cardiac Resynchronization Therapy; Ablation of Atrial Arrhythmia in Patients with Heart Failure; Ablation of Ventricular Arrhythmic in Patients with Heart Failure; and Autonomic Modulation.