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The development of modern psychopharmacology was triggered by two major discoveries: the psychomimetic effects of lysergic acid diethylamide (LSD-25) in 1943 and the therapeutic effects of chlorpromazine in 1952. In his opening address to the 1st CINP Congress in Rome, Rothlin pointed out that these discoveries gave "a great impetus for any kind of scientific approach to brain research" and had "revolutionary consequences in the treatment of psychotic patients". The incentive they provided "was not limited to theoretical and practical medical sciences but caused an even greater stimulus to the imagination of chemists, leading to the production of new compounds with a speed that neither pharm...
This volume highlights recent progress in understanding the biology of neurological and psychiatric disorders and developing more effective drug therapies. Included are reports on new strategies for treatment of Parkinson's disease, refractory epilepsy, and postnatal and childhood psychiatric disorders, as well as on the biology and treatment of dementia and related conditions, drug addiction and alcoholism, post-traumatic stress, impulse control disorders, panic, and anxiety states. Leading experts reassess the mechanisms of action and the rational use of antidepressants, antipsychotics, lithium and other mood stabilizers, and anxiolytics and present extensive findings on new drugs such as atypical antipsychotics, reversible MAO-inhibitors, anxiolytics not acting at the benzodiazepine receptor, and antiepileptics that are effective as mood stabilizers. Other topics covered include brain imaging studies, molecular genetics of CNS diseases, stress-induced neurochemical changes, molecular aspects of receptors and psychotropic drugs, and biological markers for psychiatric diseases.
First multi-year cumulation covers six years: 1965-70.
Recent Advances In Neuropsychopharmacology contains selected papers from the 12th Congress of the Collegium Internationale Neuro-Psychopharmacologicum held in Gõteborg, Sweden, 22-26 June 1980. The 47 papers in the volume are organized into six parts. The papers in Part I deal with the subject of psychostimulants in psychiatric research. Topics covered include the effect of chronic d-amphetamine and chronic apomorphine treatment on non-human primate social and solitary behavior; and the behavioral effects of dopamine agonists. Part II assesses the prescription of psychotropic drugs by general practitioners. Part III examines blood platelets as a model system for central monoaminergic neurons. Part IV focuses on anxiety pathways in the brain. Part V considers prospects for a biochemical classification system in psychiatry. Part VI presents pharmacokinetic studies of psychotropic drugs. Part VI contains two papers on the renal function and renal histology of lithium patients on maintenance lithium therapy and pre-lithium patients; and the treatment of refractory schizophrenia.
First multi-year cumulation covers six years: 1965-70.