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This cross-disciplinary book documents the key research challenges in the mathematical sciences and physics that could enable the economical development of novel biomedical imaging devices. It is hoped that the infusion of new insights from mathematical scientists and physicists will accelerate progress in imaging. Incorporating input from dozens of biomedical researchers who described what they perceived as key open problems of imaging that are amenable to attack by mathematical scientists and physicists, this book introduces the frontiers of biomedical imaging, especially the imaging of dynamic physiological functions, to the educated nonspecialist. Ten imaging modalities are covered, from the well-established (e.g., CAT scanning, MRI) to the more speculative (e.g., electrical and magnetic source imaging). For each modality, mathematics and physics research challenges are identified and a short list of suggested reading offered. Two additional chapters offer visions of the next generation of surgical and interventional techniques and of image processing. A final chapter provides an overview of mathematical issues that cut across the various modalities.
At the heart of every medical imaging technology is a sophisticated mathematical model of the measurement process and an algorithm to reconstruct an image from the measured data. This book provides a firm foundation in the mathematical tools used to model the measurements and derive the reconstruction algorithms used in most imaging modalities in current use. In the process, it also covers many important analytic concepts and techniques used in Fourier analysis, integral equations, sampling theory, and noise analysis.This text uses X-ray computed tomography as a "pedagogical machine" to illustrate important ideas and incorporates extensive discussions of background material making the more a...
This graduate textbook explains image geometry, and elaborates on image enhancement in spatial and frequency domain, unconstrained and constrained restoration and restoration from projection, and discusses various coding technologies such as predictive coding and transform coding. Rich in examples and exercises, it prepares electrical engineering and computer science students for further studies on image analysis and understanding.
In 1994, in my role as Technical Program Chair for the 17th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, I solicited proposals for mini-symposia to provide delegates with accessible summaries of important issues in research areas outside their particular specializations. Terry Peters and his colleagues submitted a proposal for a symposium on Fourier Trans forms and Biomedical Engineering whose goal was "to demystify the Fourier transform and describe its practical application in biomedi cal situations". This was to be achieved by presenting the concepts in straightforward, physical terms with examples drawn for the parti cipants work in physiological signal analysis and medical imaging. The mini-symposia proved to be a great success and drew a large and appreciative audience. The only complaint being that the time allocated, 90 minutes, was not adequate to allow the participants to elaborate their ideas adequately. I understand that this feedback helped the authors to develop this book.
Bioimaging is a sophisticated, non-invasive, and non-destructive technique for the direct visualization of biological processes. Highly luminescent quantum dots combined with magnetic nanoparticles or ions form an exciting class of new materials for bioimaging. These materials can be prepared in cost-effective ways and show unique optical behaviors. Magnetic Quantum Dots for Bioimaging explores leading research in the fabrication, characterization, properties, and application of magnetic quantum dots in bioimaging. Covers synthesis, properties, and bioimaging techniques Discusses modern manufacturing technologies and purification of magnetic quantum dots Explores thoroughly the properties and extent of magnetization to various imaging techniques Describes the biocompatibility, suitability, and toxic effects of magnetic quantum dots Reviews recent innovations, applications, opportunities, and future directions in magnetic quantum dots and their surface-decorated nanomaterials This comprehensive reference offers a road map of the use of these innovative materials for researchers, academics, technologists, and advanced students working in materials engineering and sensor technology.
This book surveys the main mathematical ideas and techniques behind some well-established imaging modalities such as X-ray CT and emission tomography, as well as a variety of newly developing coupled-physics or hybrid techniques, including thermoacoustic tomography. The Radon Transform and Medical Imaging emphasizes mathematical techniques and ideas arising across the spectrum of medical imaging modalities and explains important concepts concerning inversion, stability, incomplete data effects, the role of interior information, and other issues critical to all medical imaging methods. For nonexperts, the author provides appendices that cover background information on notation, Fourier analysis, geometric rays, and linear operators. The vast bibliography, with over 825 entries, directs readers to a wide array of additional information sources on medical imaging for further study.
Computer-assisted imaging with radiation (x- and gamma rays) is an integral part of modern medical-diagnostic practice. This imaging technology is also slowly finding its way into industrial applications. Although the technology is well developed, there is a need for further improvement to enhance image quality, reduce artifacts, minimize patient radiation exposure, compete with and complement other imaging methods (such as magnetic resonance imaging and ultrasonics), and accommodate dense and large objects encountered in industrial applications. Scientists and engineers, attempting to progress this technology, are faced with an enormous amount of literature, addressing the imaging problem f...
This volume contains presentations by eminent researchers: Statistical Inference for Spatial Processes; Image Analysis; Applications of Spatial Statistics in Earth, Environmental, and Health Sciences; and Statistics of Brain Mapping. They range from asymptotic considerations for spatial processes to practical considerations related to particular applications including important methodological aspects. Many contributions concern image analysis, mainly images related to brain mapping.
Multiscale Modelling in Biomedical Engineering Discover how multiscale modeling can enhance patient treatment and outcomes In Multiscale Modelling in Biomedical Engineering, an accomplished team of biomedical professionals delivers a robust treatment of the foundation and background of a general computational methodology for multi-scale modeling. The authors demonstrate how this methodology can be applied to various fields of biomedicine, with a particular focus on orthopedics and cardiovascular medicine. The book begins with a description of the relationship between multiscale modeling and systems biology before moving on to proceed systematically upwards in hierarchical levels from the mol...