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Xenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed. This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.
Some developing biotechnologies challenge accepted legal and ethical norms because of the risks they pose. Xenotransplantation (cross-species transplantation) may prolong life but may also harm the xeno-recipient and the public due to its potential to transmit infectious diseases. These trans-boundary diseases emphasise the global nature of advances in health care and highlight the difficulties of identifying, monitoring and regulating such risks and thereby protecting individual and public health. Xenotransplantation raises questions about how uncertainty and risk are understood and accepted, and exposes tensions between private benefit and public health. Where public health is at risk, a precautionary approach informed by the harm principle supports prioritising the latter, but the issues raised by genetically engineered solid organ xenotransplants have not, as yet, been sufficiently discussed. This must occur prior to their clinical introduction because of the necessary changes to accepted norms which are needed to appropriately safeguard individual and public health.
This book addresses ethical conflicts arising from saving the lives of patients who need a transplant while treating living and dead donors, organ sellers, animals, and embryos with proper moral regard. Our challenge is to develop a better world in the light of debatable values and uncertain consequences.
In this revised edition of Moral Conflicts of Organ Retrieval: A Case for Constructive Pluralism, Charles Hinkley elaborates on his moral philosophy of constructive pluralism and updates the literature on organ retrieval strategies. Hinkley challenges a deeply entrenched moral triad: 1) moral values are comparable; 2) the weighing metaphor helps us conceptualize decisions regarding conflicting values; and 3) there is a single best discoverable response to a moral decision. This book offers an alternative—cases of incomparability, a constructing or making metaphor, and multiple permissible responses to some moral questions. Constructive pluralism has important implications for organ transplantation, health, and ethics.
Organ transplantation raises singularly difficult ethical and legal issues in its requirement for donated organs. Strategies to facilitate supply in the face of increasing demand must be ethically sound and subject to an appropriate and effective regulatory framework. Professor David Price reviews the ethical principles and positions underpinning such law and policies, probing for coherence, consistency and justification. The book incorporates a comprehensive analysis of existing laws and policies governing transplantation practices around the world. It examines the meaning of death, cadaver organ procurement policies, use of living donors, trading in human organs, experimental transplant procedures and xenotransplantation. Drawing upon a wide range of disciplinary and empirical materials Price explores the balance between the interests of donors, recipients, clinicians, and society, identifying the specific challenges of this subject and seeking to guide current practices and future developments in the context of cultural diversity and pluralistic societies.
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Supply your library with the best collection of resources on animal issues! Animals are the Issue: Library Resources on Animal Issues is a guide to books, journals, and Web sites on historic and modern animal treatment. Expert librarians and scholars provide helpful resources showing what ideals and practical solutions exist in animal rights and welfare debates. With this book, students, philosophers, and politicians can find the best of written and electronic resources about the protection and ethical use of animals by humankind. Animals are the Issue stands alone as a source for locating materials on animal protection and welfare. This valuable guide will help librarians save time and mone...
The new reproductive technologies (NRTs) have given rise to new ethical questions that are widely debated. This book, the outcome of a European Union-wide collaborative process, draws on the experience and expertise of ethicists, lawyers, and clinical practitioners and focuses on some of the "burning issues" in different European countries. These include: donor insemination; surrogacy; preimplantation genetic diagnosis; embryo research; access to IVF treatment; and parental, professional and social responsibility. Familiar notions such as quality of life, parenthood, mothering, responsibility and personal identity surface at many points throughout the book and are refashioned to accommodate new questions. This book introduces and probes ethical questions and challenges in a hands-on way by working through relevant case studies with key commentaries and activities. It engages the reader directly in ethical reasoning and decision-making and provides clear explanations, insightful commentaries and informed debate on NRTs.