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Creating Coordination in the Cerebellum provides a multidisciplinary collection of chapters on the cerebellum with topics covering the entire spectrum from development and molecular neurobiology, cell physiology and plasticity to motor control, system physiology, functional imaging and pathology. The book not only presents novel discoveries obtained with recently developed technologies, but also gives new general concepts in global issues of cerebellar development and functions. By doing so it sets the standard for cerebellar research of the 21st century.* Provides a complete overview of current cerebellar research* Includes color illustrations* Contains contributions from renowned cerebellar scientists
Over the past thirty-five years, there has been an explosive increase in scientists' ability to explain the structure and functioning of the human brain. While psychology has advanced our understanding of human behavior, various other sciences, such as anatomy, physiology, and biology, have determined the critical importance of synapses and, through the use of advanced technology, made it possible actually to see brain cells at work within the skull's walls. Here Jean-Pierre Changeux elucidates our current knowledge of the human brain, taking an interdisciplinary approach and explaining in layman's terms the complex theories and scientific breakthroughs that have significantly improved our understanding in the twentieth century.
Continuing progress has been made in understanding the brain at the molecular, anatomic, and physiological levels in the years following the "Decade of the Brain," with the results providing insight into the underlying basis of many neurological disease processes. In Neuroscience in Medicine, Third Edition, a distinguished panel of basic and clinical investigators, noted for their teaching excellence, provide thoroughly updated and revised chapters to reflect these remarkable advances. Designed specifically for medical students and allied health professionals, this up-to-date edition alternates scientific and clinical chapters that explain the basic science underlying neurological processes ...
It is appropriate at the outset of this book to pose a question that was often asked --of the organizers before the meeting took place and later among those who participated in the meeting -- "What is meant by 'Systems Approaches' in the study of developmental neurobiology?" The answer, as we originally conceived it, can be succinctly summarized by the word "interactions". That brief epithet was expanded during the general discussion portion of the meeting, where the following definition was offered: "Systems approaches in developmental neurobiology are unified by attention to the emergent properties of the developing system under investigation and by a focus on the aspects of development of...
Thyroid hormone signaling has been known for a long time to be required for proper neurodevelopment and the maintenance of cognitive functions in the adult brain. As thyroid hormone excess or deficiency is usually well handled by clinicians, research dedicated to the neural function of thyroid hormone, have not been a priority within the field. This is changing mainly for two reasons. First, new genetic diseases have been discovered, altering thyroid hormone signaling in brain (THRA, MCT8, SBP2), with neurodevelopmental consequences which are currently incurable. Second, there is a growing concern that exposition of the general population to environmental chemicals able to interfere with thy...
First multi-year cumulation covers six years: 1965-70.
Neuroscience has paid only little attention to decision-making for many years. Although no field of science has cohered around this topic, a variety of researchers in different areas of neuroscience ranging from cellular physiology to neuropsychology and computational neuroscience have been engaged in working on this issue. Thus, the time seemed to be ripe to bring these researchers together and discuss the state of the art of the neurobiology of decision-making in a broad forum. This book is a collection of contributions presented at that forum in Paris in October 1994 organized by the Fondation IPSEN.
This book, together with the next two volumes to follow, offers the scientific community the works and thoughts of Santiago Ramón y Cajal. The text is a faithful rendition of the original Spanish version, with additional facts taken from the French translation. Both of these are currently quoted an average of 200 times a year in the scientific literature. This collection will represent the "definitive Cajal" for scientists and scholars interested in the original thoughts of probably the most prominent neuroscientist of all time.
In this book, laboratory leaders on cerebellar neuroscience have revised the present body of knowledge about cerebellum anatomy and function. The trip throughout the cerebellar vineyard organization starts from the causal study of morphogenesis (that is, the molecular and cellular mechanisms underplaying form generation) to the molecular mechanism regulation cellular differentiation: Basson, Dusart, Hawkes, Martinez and Rosi’s groups contributions. Then, neurodevelopmental anomalies associated with structural disorganization are revised in Jissendi and Batkovich’s group reviews, describing and discussing pathogenic processes. Finally, functional mechanisms of cerebellar circuits involved in motor learning are revised by Delgado-Garcia and Armengol’s group contribution.