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Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis. However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds. Their existence explains many of the enigmas of microbial infection and a better grasp of the pr...
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The GB Rail Timetable contains rail services operated over the GB rail network, together with rail and shipping connections with Ireland, the Isle of Man, the Isle of Wight and the Channel Islands. Published by TSO with permission from Network Rail (owners of Britain's national railway and stations) the GB Rail Timetable - Winter Edition 11 holds details on passenger services operated by the Train Companies, who work together closely to provide a coordinated rail network offering a range of travel opportunities.
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