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Hypoxia is and remains a major public health issue in many populated mountainous areas all over the world. This book is directly derived from a NATO-sponsored international meeting on problems of high altitude medicine and biology, which was held on the shores of lake Issyk-Kul, in Kyrghyzstan, in 2006. Overall, the meeting was an ideal mix of cell biology, integrative physiology and medical applications.
This is the sixth set of Handbook of Porphyrin Science.This 5-volume set provides a comprehensive review of the most up-to-date research on porphyrin, heme and chlorophyll biochemistry, as well as applications to biomedicine and bio-inspired energy. In-depth coverage of topics along with perspectives on outstanding questions and future research directions by the authors make these volumes an essential resource for both beginning and advanced investigators in the field. It is also suitable for non-experts in porphyrin, who wish to have an overview of the fundamental discoveries and breakthroughs in the porphyrin arena related to medicine and bio-inspired energy.Bringing together the biochemistry of porphyrin-binding proteins and their clinical relevance and applications to medicine and renewable energy, this set provides readers with an integrated coverage of porphyrin biochemistry. At the same time, it challenges readers with new questions and perspectives of research regarding the role of porphyrin biochemistry in the future of medicine and renewable energy.
This book constitutes the refereed post-conference proceedings on Learning and Intelligent Optimization, LION 15, held in Athens, Greece, in June 2021. The 30 full papers presented have been carefully reviewed and selected from 35 submissions. LION deals with designing and engineering ways of "learning" about the performance of different techniques, and ways of using past experience about the algorithm behavior to improve performance in the future. Intelligent learning schemes for mining the knowledge obtained online or offline can improve the algorithm design process and simplify the applications of high-performance optimization methods. Combinations of different algorithms can further improve the robustness and performance of the individual components.
The goal of enterprise integration is the development of computer-based tools that facilitate coordination of work and information flow across organizational boundaries. These proceedings, the first on EI modeling technologies, provide a synthesis of the technical issues involved; describe the various approaches and where they overlap, complement, or conflict with each other; and identify problems and gaps in the current technologies that point to new research.The leading edge of a movement that began with computer-aided design/computer-aided manufacturing (CAD/CAM), EI now seeks to engage the development of computer-based tools to control not only manufacturing but the allied areas of mater...
The first book dedicated explicitly to the care of elderly patients with rheumatic diseases, this comprehensive resource is a practical guide for navigating the medical concerns of these complex patients. While patients over 65 years of age comprise roughly 15% of the population, they consume about 50% of rheumatology resources. This book presents current clinical practices with an eye toward achieving economically sustainable models of care. The world’s leading authorities have come together to cover the full spectrum of rheumatic diseases, the immune system in aging, and ultrasound evaluation and arthrocentesis. The book also addresses the milieu of co-morbidities that the clinician may ...
South America's Andean highlands have seen the rise and decline of several impressive, indigenous civilizations. Separated somewhat in time and place, each developed its distinctive socio-cultural accouterments but all shared a need to adjust to the individual, societal and environmental limitations imposed by life at high altitude. Partial oxygen pressure, temperature and humidity fall systematically as altitude rises, but there are other changes as well. Darwin, Forbes, von Humboldt, von Tschudi and other naturalists of the eighteenth and nineteenth centuries who weaved their way through South America commented repeatedly on the tolerance or apparent indifference of the indigenes to the ri...
This book presents the latest research, theoretical methods, and novel applications in the field of Health 5.0. The authors focus on combating COVID-19 or other pandemics through facilitating various technological services. The authors discuss new models, practical solutions, and technological advances related to detecting and analyzing COVID-19 or other pandemic based on machine intelligence models and communication technologies. The aim of the coverage is to help decision-makers, managers, professionals, and researchers design new paradigms considering the unique opportunities associated with computational intelligence and Internet of Medical Things (IoMT). This book emphasizes the need to analyze all the information through studies and research carried out in the field of computational intelligence, communication networks, and presents the best solutions to combat COVID and other pandemics.