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Our goal for this book is to examine the contemporary therapy of rheumatoid arthritis (RA) from the increasingly important perspective of impact upon quality of life, costs and long-term health outcomes. For too long the focus has been on short term, symptomatic, and surrogate indicator outcomes. Yet RA is a life-long disor der with the majority of impact on an individual patient many years following onset. Further, even in the short-term, researchers and rheumatologists have tended to emphasize measurements of disease activity such as joint counts, ESR and physi cian's opinion as to the amount of disease activity present. It is only relatively recently that measures of structural damage, qu...
Written and edited by the foremost experts in knee surgery, this definitive two-volume reference provides comprehensive coverage of the evaluation and surgical management of problems of the adult knee. In 117 detailed chapters, the text covers basic science, clinical science, soft tissue injury of the knee, tendon and ligament surgery, osteochondral injury to the knee, patella femoral disorders, alternatives to arthroplasty for knee arthritis, primary total knee arthroplasty, perioperative management in total knee replacement, complications of total knee replacement, revision total knee arthroplasty, and future developments.
These two volumes contain the papers presented at a North Atlantic Treaty Organization (NATO) Advanced Study Institute held on September 22-28, 1979 in Monte Carlo, Monaco. The conference was entitled "In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities." This international conference presented an opportunity for the participants to exchange informa tion and ideas on the current approaches (both scientific and po litical) for toxic assessment of environmental agents. The poten tial health effects of these compounds as well as future needs in the environmental research field were discussed. The scientific content of the conference seminars included an overview ...
The book combines comprehensive coverage of various aspects of hypertension with guidance in conveying important concepts, knowledge, and advice to patients. The result is a highly useful tool for achieving clinically successful, cost-effective pharmaceutical care for hypertensive patients, and for reducing the morbidity and mortality associated with this devastating disease state. Book jacket.
The Encyclopedia of Medical Decision Making presents state-of-the-art research and ready-to-use facts sorting out findings on medical decision making and their applications.
The profession of paramedicine is rapidly expanding and primary research relating to prehospital interventions is exploding worldwide. This new book provides, for the first time, a meaningful and easy to understand guide to research specifically tailored for paramedics. Written by experts in research, medicine and paramedicine, Introducing, Designing and Conducting Research for Paramedics introduces the reader to the concepts of research through real-life examples. The structure follows a logical sequence from an overview of the research process to how to generate, consume and implement evidence. This book will be a valuable resource for paramedics and prehospital clinicians at any level, wo...
This book presents a comprehensive overview of pediatric thyroid diseases and thus provides a useful tool for clinical problem solving. Opinion leaders in the field present reviews on all relevant diseases of the hypothalamic-pituitary-thyroid axis. Sixteen chapters cover topics ranging from fetal thyroidology, congenital hypothyroidism, central hypothyroidism, inherited defects of thyroid hormone action, cell transport and metabolism to iodine deficiency, autoimmune thyroid disease and thyroid tumors. Written by clinicians, the chapters provide in-depth information and current guidelines for clinical problems encountered in pediatric thyroidology. As a unique feature, a case seminar collection for each chapter presents typical patient histories providing key learning points and key references for clinical problem solving in family medicine, pediatric endocrinology and medical genetics. Providing a succinct update on clinical pediatric thyroidology, this book is an essential tool for pediatric and adult endocrinologists, as well as for general practitioners, pediatricians and medical geneticists.
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