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The Enzymes
The Enzymes
The Enzymes
Conteúdo: Hydrolysis: peptide bonds.
Drug Design
Drug Design, Volume III covers the mode of action of biologically active compounds. The book discusses microbial transformations that have been used in the preparation of drugs or closely related substances; the use of linear free energy parameters and other experimental constants in structure-activity studies; and the mode of action of anticoagulants structurally and functionally related to vitamin K. The text also describes the design of beta-blocking drugs, biologically active acridines, local anesthetics, and insect chemosterilants. The molecular approach for designing inhibitors to enzymes involved in blood clotting is also considered. Chemists, pharmacologists, and people involved in drug design.
Amino Acids, Peptides and Proteins
Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 90 years The Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The A...
Comprehensive Medicinal Chemistry II
The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organis...
Aluminium and Alzheimer's Disease
The subject of aluminium and Alzheimer's disease has been plagued with controversy. This controversy has served to obscure much of the scientific research in this field, and subsequently has obscured the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease. This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this knowledge on a link between aluminium and Alzheimer's disease. The subject areas of the chapters were chosen to reflect the myriad of ways that aluminium is known to ...
Chemical Biology, Selected Papers Of H G Khorana (With Introductions)
The first two chapters of this invaluable book trace the developments of the chemistry and macromolecular structures, respectively, of proteins and nuclei acids. Similarly, the introductions to the succeeding chapters review, step by step, the historical landmarks in the topics covered. These include discoveries of biological phosphate esters, nucleotides and nucleotide coenzymes (important in intermediary metabolism), the nature of the genetic material and biological synthesis of proteins, formulation of the problem of the genetic code, and perspectives on bioenergetics.The selected papers illustrate the developments of the chemical synthesis of nucleotides and nucleotide coenzymes of ribo-...
Amino Acids and Peptides
Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The A...
The Terrestrial Environment, B
Handbook of Environmental Isotope Geochemistry, Volume 2: The Terrestrial Environment, B focuses on the processes, methodologies, principles, and approaches involved in isotope geochemistry. The selection first elaborates on mathematical models for the interpretation of environmental radioisotopes in groundwater systems; isotopes in cloud physics; and environmental isotopes in lake studies. Discussions focus on water balance studies of lakes, isotopic fractionations during evaporation of water, study of hailstone growth mechanisms by means of isotopic analyses, isotopic effects during growth of individual elements, and models and their hydrological significance. The text then takes a look at...
Road Dogs
“Road Dogs is terrific, and Elmore Leonard is in a class of one.” —Dennis Lehane, author of Shutter Island and Mystic River “You know from the first sentence that you’re in the hands of the original Daddy Cool....This one’ll kill you.” —Stephen King Elmore Leonard is eternal. In Road Dogs, the PEN USA Lifetime Achievement Award winner and “America’s greatest crime master” (Newsweek) brings back three of his favorite characters—Jack Foley from Out of Sight, Cundo Rey from La Brava, and Dawn Navarro from Riding the Rap—for a twisting, explosive, always surprising masterwork of crime fiction the San Francisco Chronicle calls, “a sly, violent, funny and superbly written story of friendship, greed, and betrayal.”
