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It has been 10 years since Plenum included a series of reviews on bacte riophages, in Comprehensive Virology. Chapters in that series contained physical-genetic maps but very little DNA sequence information. Now the complete DNA sequence is known for some phages, and the se quences for others will soon follow. During the past 10 years two phages have come into common use as reagents: A phage for cloning single copies of genes, and Ml3 for cloning and DNA sequencing by the dideoxy termi nation method. Also during that period the use of alternative sigma fac tors by RNA polymerase has become established for SPOl and T4. This seems to be a widely used mechanism in bacteria, since it has been im...
Takes the reader through the origins of catalysis in RNA and necessarily includes significant discussion of structure and folding. The main focus of the book concerns chemical mechanism with extensive comment on how, despite the importance of RNA catalysis in the cell, its origins are still poorly understood and often controversial. The reader is given an outline of the important role of RNA catalysis in many aspects of cell function, including RNA processing and translation.
This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.
The celebrated authors present an in-depth overview of the molecular structures and mechanisms that underlie the utilization of genetic information by complex organisms. They emphasize the experimental aspects of molecular genetics, offering a complete introduction to both principles and methods. "Excellent, suitably detailed and superbly written." Philip Leder, Harvard Medical School
Bem-vindo ao Bestiário do Old Dragon, um livro com presas e garras. Aqui você vai encontra mais de 200 criaturas totalmente detalhadas, com descrições, comportamento, ecologia e estatísticas de jogo dispostas de forma organizada, didática e precisa. Um compêndio completo de ameaças para você tornar seus combates de Old Dragon cada vez mais heroicos, fantásticos e empolgantes. Neste Livro você encontrará: - Mais de 200 monstros com blocos de estatísticas e descricões, completas - Sugestões e dicas para criar seus próprios monstros; - Modelos, uma nova forma de transformar criaturas antigas em novos desafios; - Listas completas para consulta rápida com monstros por Dado de Vida, Habitat e Conceito; - Tabelas de encontros prontas para todos os níveis de personagem; - Nova tabela de Afastar Mortos-Vivos; - Ficha especial para suas novas criações monstruosas Autor: Fabiano Neme Idioma: Português Número de páginas: 224 ISBN: 978-85-65146-06-7 Dimensões: 21×14 cm (A5)
This book provides the first and only comprehensive description and detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies, which are tied together through their frequent fusion and coevolution, have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations.
Kabala'nın yaratılmasından çok önce tapınılan ve çağrılan eski çağlara ait güçler vardır. Bunlar Sümer inancındaki kadimlerdir ve Aleister Crowley'in majisinde ve H.P. Lovecraft'ın mitosunda yaşarlar. Dünyayı bir kez daha yönetmek için kapının hemen ardında beklemektedirler...