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The temporal order of physiological functions such as sleep/wakefulness is regulated by the circadian clock. This intrinsic clock starts ticking in the embryo and matures during development, with attenuation of the clock function in the elderly, illustrated by attenuation of synchrony, entrainment, and outputs of cellular circadian rhythms in the SCN. This age-related diminution can contribute to the emergence of diseases, such as sleep disorders, infertility, diabetes, mental disorders etc. Over the course of our lives, a variety of internal and external factors are under the influence of the circadian clock. This inherent developmental plasticity of the circadian system is critical for the...
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Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future researchChapters are extensively referenced to provide readers with a comprehensive list of resources on the topics coveredAll chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist - Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
This book discusses recent brain research and the potentially dangerous dual-use applications of the findings of these research projects. The book is divided into three sections: Part I examines the rise in dual-use concerns within various state’s chemical and biological non-proliferation regime’s during this century, as well as the rapid technologically driven advances in neuroscience and the associated possible misuse considerations in the same period. Part II reviews the brain research projects in the EU, USA, Japan, China and several other countries with regard to their objectives, achievements and measures to deal with the problem of dual-use. Part III assesses the extent to which the results of this civil neuroscience work, which is intended to be benign, are being, and could be protected against future hostile applications in the development of novel chemical and biological weapons.
Reality is tough, but...surely, the future must be bright. Handa-sensei has returned from Tokyo with a new declaration--he's going to start his own calligraphy school! But will he find any students!? But when an unusually cold winter brings rare snow to the island, is Handa prepared to hibernate the time away...?
The battle at the base of the Mermerai mountains draws to a close following the entrance of the silver-haired Yogi. However, even after the trouble ends, Silver Yogi refuses to revert to Yogi's normal self! Aboard the 2nd Ship, Nai awaits Gareki's return...Later, a visitor turns up at Uro's door--Azana. Though his thoughts have remained with Dr. Akari, Azana has been working under Uro to further his research on Varuga. Meanwhile, back on Hirato's ship, Karoku reveals a shocking truth about the mysterious notebook he left behind in the Rainbow Forest. What secrets do its pages hold...?!