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Signal Transduction in Lung Cells
This reference offers detailed discussions of the basic aspects of signal transduction, and examines their applications in lung cell biology. Providing an overview of current research directions, Signal Transduction in Lung Cells covers: the structure and function of receptors; the structure and regulation of G proteins; second messenger systems including kinases and phosphatases; airway and alveolar cells; smooth muscle cells; inflammatory and immune cells; muscle tone, ion channels, growth factors and cytokines.;With over 1900 literature citations and figures, Signal Transduction in Lung Cells is intended as a resource for pulmonologists, physiologists, molecular and cell biologists, pharmacologists, and graduate and medical school students in these disciplines.
Metal Transporters
This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise
Store-Operated Calcium Channels
Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Co-Transport Systems
Current Topics in Membranes is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. In this volume, researchers are encouraged to fully explore topics and research related to co-transport systems. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes. - Field is cutting-edge and a lot of the information is new to research community - Wide breadth of topic coverage - Contributors of high renown and expertise
Current Topics in Membranes
Current Topics in Membranes
Membrane Protein-Cytoskeleton Interactions
The plasma membrane acts as both a boundary and a site of exchange between the outside and the inside of a cell. The cytoskeleton plays essential roles in delineating membrane protein distributions, in defining structural and functional domains in the plasma membrane, and in regulating membrane protein, and ultimately, cell function. This volume reviews the regulation of membrane protein distribution, organization, and function at the plasma membrane by the cytoskeleton. Discussions also include the roles of cytoskeleton in the structural and functional organization of membranes and membrane proteins with emphasis on key problems, the current status of understanding, experimental approaches, and future directions.
Ionic Channels in Cells and Model Systems
This book is based on a series of lectures for a course on ionic channels held in Santiago, Chile, on November 17-20, 1984. It is intended as a tutorial guide on the properties, function, modulation, and reconstitution of ionic channels, and it should be accessible to graduate students taking their first steps in this field. In the presentation there has been a deliberate emphasis on the spe cific methodologies used toward the understanding of the workings and function of channels. Thus, in the first section, we learn to "read" single channel records: how to interpret them in the theoretical frame of kinetic models, which information can be extracted from gating currents in re lation to the ...
