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Restoring Functional Behaviors After Traumatic Peripheral Nerve Injuries
Peripheral nerve injuries (PNIs) by trauma are the most common neuronal injury in civilian and military populations and significantly burden health care systems. Mammals (including humans) with PNIs experience: (1) immediate loss of sensory and motor functions mediated by the denervated target tissues; (2) rapid (3-7d) Wallerian Degeneration (WD) of severed distal axonal segments; and, (3) slow (~1mm/day) regeneration by naturally occurring axonal outgrowths from surviving, severed proximal stumps that produce poor (if any) functional recovery because of slow axonal regeneration for long distances and lack of axonal guidance. Denervated muscle fibers and sensory organs often atrophy before any re-innervation can occur.
The Kinsey Institute
An in-depth history of Alfred Kinsey’s groundbreaking Institute for Sex Research and the cultural awakening it inspired in America—“it has no rival” (Angus McLaren). While teaching a course on Marriage and Family at Indiana University, biologist Alfred Kinsey noticed a surprising dearth of scientific literature on human sexuality. He immediately began conducting his own research into this important yet neglected field of inquiry, and in 1947, founded the Institute for Sex Research as a firewall against those who opposed his work on moral grounds. His frank and dispassionate research shocked America with the hidden truths of our own sex lives, and his two groundbreaking reports —Sex...
Developmental Time and Timing
Many theorists now believe that development emerges out of the coming together of multiple influences on the developing organism. To understand development, not only is it important to identify these influences, but it is necessary to describe their relationship to one another. In this dynamic view of development, emergent organization is the result of the components of development coming together. Timing is concerned with the relationship between components that have different rates of development. This book brings together the work of several investigators who have contributed to our understanding of the impact of timing on development through the examination of different functions and dif...
Research Grants
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The College
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Current Catalog
First multi-year cumulation covers six years: 1965-70.
Effect of Environmental Air Temperature and Composition on the Development of the Norway Rat (Rattus Norvegicus)
In the wild, Norway rats successfully reproduce in climates ranging from the arctic to the tropics. The offspring are born and reared in burrows that offer limited protection from the surface environmental temperature and generally have elevated carbon dioxide concentrations. Because the young are born with little insulation, poor motor coordination, and immature thermal and respiratory regulatory abilities, the air properties of the postnatal environment present considerable thermal and respiratory challenges for rat neonates. Yet, little was known about if, when, and how the air temperature and composition of the postnatal environment affects the development of the young. Therefore, the ef...
APS Observer
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The Retinal Müller Cell
The human brain contains more than a billion neurons which interconnect to form networks that process, store, and recall sensory information. These neuronal activities are supported by a group of accessory brain cells coll- tively known as neuroglia. Surprisingly, glial cells are ten times more - merous than neurons, and occupy more than half the brain volume (Hydén, 1961). Although long considered a passive, albeit necessary, component of the nervous system, many interesting and unusual functional properties of glial cells are only now being brought to light. As a result, the status of these cellular elements is approaching parity with nerve cells as a subject for experimental study. The t...
