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The underlying idea that cancer is a genetic disease at the cellular level was postulated over 75 years ago when Boveri hypothesised that the malignant cell was one that had obtained an abnormal chromatin content. However, it has been only the last decade where enormous strides have been made toward understanding neoplastic development. Explosive growth in the discipline of cancer genetics is so rapid that any attempt to review this subject becomes rapidly outdated and continuous revisions are warranted. Conclusive evidence has been reached associating specific chromosomal abnormalities to various cancers. We have just begun to characterise the genes, which are involved in these consistent c...
Praise for the Series:"Full of interest not only for the molecular biologist - for whom the numerous references will be invaluable - but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal - Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology - Contributions from leaders in their fields - Abundant references
A thrilling read Customer Rating See Detailed Ratings Posted August 18, 2010, 10:13 PM EST: A thrilling read, "In One Hand" quickly takes you by the hand and leads you through the early adult life of the main character, Tony Sardelli. A Brooklyn born only child of very loving Italian parents, Tony is first headed to the U.S.Army. From here he swiftly picks you up and engulfs you in both the very good and very hard times of his early adulthood. Army life, N.Y.C. Police Department, friendship, marriage, devotion, and integrity all displayed with the undertones of both his loving, Christian Italian upbringing and his tough Brooklyn attitude keeps the reader engulfed in this story. The author's ...
Recent Progress in Hormone Research, Volume 46 provides a superior summary of the developments in the field of hormone research. The book discusses the molecular basis of androgen insensitivity; the tissue-specific expression of the growth hormone gene and its control by growth hormone factor-1; and the molecular characterization of mammalian tachykinin receptors and a possible epithelial potassium channel. The text also describes the properties of the guanylate cyclase receptor family; insulin-like growth factor-binding proteins; and growth hormone receptor and binding protein. Mutations in the insulin receptor gene in genetic forms of insulin resistance; the characteristics of the cAMP response unit; and the role and secretion of inhibin in the rat are also considered. The book further tackles the structure of the lutropin/choriogonadotropin receptor and the gene for multiple endocrine neoplasia type 2a. Endocrinologists, physiologists, and biochemists will find the text invaluable.
This is the third edition of a book conceived and collated by Ken Cato to present favourite works of some of the world's leading graphic designers. Knowing how difficult it was to choose his own favourite pieces, Cato has again set an almost impossible t
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Cases of Teachers’ Data Use addresses applications of student data beyond theoretical, school-, and district-level examinations by presenting case studies of teachers’ data use in practice. Within the context of data-driven education reform policies, the authors examine the effective and ineffective ways that teachers make use of student data in instruction, evaluation, and planning. Promising practices, based on the empirical research presented, offer strategies and routines for sound data use that can be applied in schools. Chapters written by scholars from diverse methodological perspectives offer readers multiple lenses to use in considering issues of data use such that current theoretical assumptions may be challenged and the field advanced. This uniquely focused yet comprehensive work is an indispensable resource for researchers and students interested in classroom assessment and for professionals looking to support teachers’ use of student performance data for adaptive instruction.