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The Nidoviruses
  • Language: en
  • Pages: 500

The Nidoviruses

This book is the proceedings of the VIII International Symposium on Nidoviruses (Coronaviruses and Arteriviruses), held May 20-25, 2000, in Philadelphia, Pennsylvania, USA. This comprehensive new book summarizes current knowledge concerning this group of viruses. It details the genomic structure of the viruses, the mechanism of their entry into cells, their mechanism of replication, RNA synthesis, and particle assembly within cells. The book also describes the epidemiology of these viruses, their pathogenesis, and the role of the immune system in interacting with these viruses.

Coronaviruses with Special Emphasis on First Insights Concerning SARS
  • Language: en
  • Pages: 241

Coronaviruses with Special Emphasis on First Insights Concerning SARS

-SARS has received much attention and coverage by the media and has a high impact on the public making this a hot research topic for scientists. -

Nirvana - A Tour Diary: My Life on the Road with One of the Greatest Bands of All Time
  • Language: en
  • Pages: 288

Nirvana - A Tour Diary: My Life on the Road with One of the Greatest Bands of All Time

Afforded the kind ofaccess a journalist can only dream of, Andy Bollen gives fansanew story focusing on the real Kurt Cobain not the angst-ridden, troubled rock star of folklore, the kind and humorous Kurt the world seldom sawWhen Nirvana first exploded onto the music scene in 1991, few people could have predicted their subsequent global impact, or thatthe band's lead singer Kurt Cobain would betransformed into one of music's most enduring and iconic figures. As drummer for the British group Captain America, one of the two support bands on Nirvana's Nevermind UK tour, Andy Bollen had a ringside seat at the exact moment that Nirvana went massive. Afforded intimate access, Bollen wrote his own...

Tough Crowd
  • Language: en
  • Pages: 307

Tough Crowd

'A must-read. Funny and utterly compelling' Jonathan Ross Having cut his teeth in music journalism, Graham Linehan became the finest sitcom writer of his generation. He captured the comedy zeitgeist not just as the co-creator of Father Ted but also with The IT Crowd and Black Books, winning five Baftas and a lifetime achievement award. Then his life took an unexpected turn. When he championed an unfashionable cause, TV commissioners no longer returned his emails, showbiz pals lost his number and his marriage collapsed. In an emotionally charged memoir that is by turns hilarious and harrowing, he lets us into the secrets of the writing room and colourfully describes the high-octane atmosphere of a sitcom set. But he also berates an industry where there was no one to stand by his side when he needed help. Bruised but not beaten, he explains why he chose the hill of women and girls' rights to die on – and why, despite the hardship of cancellation, he's not coming down from it any time soon.

George Harrison: Behind The Locked Door
  • Language: en
  • Pages: 515

George Harrison: Behind The Locked Door

Behind The Locked Door is Graeme Thomson’s rich, insightful account of George Harrison’s extraordinary life and career. This Omnibus Enhanced digital edition includes Spotify sections, detailing Harrison’s early influences, his contributions within The Beatles and the best of his solo career. Additionally, an interactive Digital Timeline leads you through a collage of music, videos and images, displaying live performances, interviews, memorabilia and more. As a Beatle, Harrison underwent a bewilderingly compressed early adulthood, buffeted by unprecedented levels of fame and success, from schoolboy to global superstar. "Beatlemania" offered remarkable experiences and opportunities, and...

Avian Influenza Virus
  • Language: en
  • Pages: 147

Avian Influenza Virus

With the growing global fear of a major pandemic, avian influenza (AI) virus research has greatly increased in importance. In Avian Influenza Virus, an expert team of researchers and diagnosticians examine the fundamental, yet essential, virological methods for AI virus research and diagnostics as well as some of the newest molecular procedures currently used for basic and applied research. They present exciting, cutting-edge new methods that focus both on studying the virus itself and on work with avian hosts, an area greatly lacking in research.

Nanostructure Design
  • Language: en
  • Pages: 296

Nanostructure Design

As one of the fastest growing fields of research in the 21st century, nanotechnology is sure to have an enormous impact on many aspects of our lives. Nanostructure Design: Methods and Protocols serves as a major reference for theoretical and experimental considerations in the design of biological and bio-inspired building blocks, the physical characterization of the formed structures, and the development of their technical applications. The chapters contributed by leading experts are divided into two sections, the first of which covers experimental aspects of nanostructure design and the second delves into computational methods. As a volume of the highly successful Methods in Molecular BiologyTM series, this collection pulls together cutting-edge protocols, written in a step-by-step, readily reproducible format certain to guide researchers to the desired results. Comprehensive and essential, Nanostructure Design: Methods and Protocols uses biological principles and vehicles on design to aid scientists in the great challenges still ahead.

Tissue Proteomics
  • Language: en
  • Pages: 231

Tissue Proteomics

In one volume this book provides useful and innovative protocols developed specifically for the proteomic profiling of human tissues. The book provides high-throughput gel-based techniques, microarrays and a number of other methods used in proteomic research. This important book will prove indispensable to investigators of biomarker discovery and therapeutic response profiling, as well as those forging new paths in the fields of theranostics and personalized medicine.

I Dream of Joni
  • Language: en
  • Pages: 295

I Dream of Joni

The eternal singer-songwriter Joni Mitchell is seen anew, portrayed through a witty and comprehensive exploration of anecdotes, quotes, and lyrics by Henry Alford, “the most graceful of humorists” (Vanity Fair) and a writer for The New Yorker. Joni Mitchell’s life, psyche, and evolving legacy are explored here in vivid technicolor—from her childhood in Saskatoon, Canada, to her arrival in Laurel Canyon that turned her into, as Alford puts it, “the bard of heartbreak and longing.” Each period of Mitchell’s life is observed via the artists, friends, family, and lovers she encountered along the way, including James Taylor, Leonard Cohen, Georgia O’Keefe, Prince, and, most significantly, Kilauren, the daughter Mitchell gave up for adoption at birth but then reconnected with decades later. Presented in the impressionistic vein of Ninety-Nine Glimpses of Princess Margaret, I Dream of Joni explores in fifty-three essays, with the author’s trademark wit and verve, the life of the legendary singer-songwriter.

Exocytosis and Endocytosis
  • Language: en
  • Pages: 407

Exocytosis and Endocytosis

In this book, skilled experts provide the most up-to-date, step-by-step laboratory protocols for examining molecular machinery and biological functions of exocytosis and endocytosis in vitro and in vivo. The book is insightful to both newcomers and seasoned professionals. It offers a unique and highly practical guide to versatile laboratory tools developed to study various aspects of intracellular vesicle trafficking in simple model systems and living organisms.