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Sexual Fluidity
Is love “blind” when it comes to gender? For women, it just might be. This unsettling and original book offers a radical new understanding of the context-dependent nature of female sexuality. Lisa M. Diamond argues that for some women, love and desire are not rigidly heterosexual or homosexual but fluid, changing as women move through the stages of life, various social groups, and, most important, different love relationships.This perspective clashes with traditional views of sexual orientation as a stable and fixed trait. But that view is based on research conducted almost entirely on men. Diamond is the first to study a large group of women over time. She has tracked one hundred women ...
Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders
Recent studies show that changes in Glutamate/GABA synapses and related pathways may determine whether the synaptic plasticity that occurs as a response to stress is adaptive or maladaptive. Findings have shed new light on the mechanisms that determine the effects of stress on cognitive and affective function. Researchers have brought a wide range of techniques to bear on the study of this problem, including cutting-edge live imaging techniques, electrophysiology, glutamate release from isolated live synaptic terminals, development of transgenic and animal models and new behavioral methods. This book provides an overview of these recent findings and of the techniques used as well as a discussion of how the molecular, cellular, and functional effects of stress may trigger or precipitate neuropsychiatric disorders such as depression, schizophrenia, anxiety and PTSD.
Neuronal Mechanisms of Memory Formation
Long-term potentiation (LTP) is by far the most dominant model for neuronal changes that might encode memory. LTP is an elegant concept that meets many criteria set up by theoreticians long before the model's discovery, and it also fits anatomical data of learning-dependent synapse changes. Since the discovery of LTP, the question has remained about how closely LTP produced in vitro by artificial stimulation of neurons actually models putative learning-induced synaptic changes. A number of recent investigations have tried to correlate synaptic changes observed after learning with changes produced by artificial stimulation of neurons. These studies have failed to find a correlation between th...
Epigenetic pathways in PTSD: how traumatic experiences leave their signature on the genome
This research topic focuses on epigenetic components of PTSD. Epigenetic mechanisms are a class of molecular mechanisms by which environmental influences, including stress, can interact with the genome to have long-term consequences for brain plasticity and behavior. Articles herein include empirical reports and reviews that link stress and trauma with epigenetic alterations in humans and animal models of early- or later-life stress. Themes present throughout the collection include: DNA methylation is a useful biomarker of stress and treatment outcome in humans; epigenetic programming of stress-sensitive physiological systems early in development confers an enhanced risk on disease development upon re-exposure to trauma or stress; and, long-lived fear memories are associated with epigenetic alterations in fear memory and extinction brain circuitry.
The Diamond Throne
Sparhawk, Pandion Knight and the Queen's champion, returns to his native land to find it overrun with evil and intrigue - and his young Queen grievously ill. As Sparhawk and his allies seek to save Ehlana, they discover the evil is even greater.
Ketogenic
Ketogenic: The Science of Therapeutic Carbohydrate Restriction in Human Health presents the most up-to-date and evidence-based science and research available in the field of TCR, with the purpose of training medical and allied healthcare professionals on the effective therapeutic use of low-carbohydrate and ketogenic nutrition in clinical practice. This book explores the appropriate, safe, and effective use of TCR to improve patient outcomes in a broad range of chronic metabolic conditions and aims to promote health. Focused on lifestyle management, health support and the treatment of diseases rooted in poor nutrition, this book explores the role of food and lifestyle modification as medicin...
The Mobility Forum
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Lies I Taught in Medical School
AN INSTANT NEW YORK TIMES BESTSELLER Modern medicine is lying to you. Discover the true science behind chronic diseases—and implement an actionable plan to take control of your health and longevity once and for all. For the first time in history, chronic diseases like diabetes, hypertension, and obesity plague our population on a global scale. From a seasoned physician, this paradigm-shifting book comprehensively explains the linked cause and exposes the misconceptions prevalent in modern medicine. In Lies I Taught in Medical School, Robert Lufkin, MD, explains that metabolic dysfunction is the common underlying cause of most chronic diseases that has been overlooked for decades, providing...
Outreach in Community Mental Health Care
Outreach in the community is the treatment of choice for the severely mentally ill in the community. It involves taking services directly to patients rather than requiring them to attend clinics and hospitals. This approach is a significant addition to routine mental health care practice and addresses the needs of marginalized communities and those that struggle to attend appointments. Outreach in Community Mental Health Care: A Manual for Practitioners has been fully updated since the last edition, providing readers with an in-depth, practical guide to mental health care in the community setting today. It addresses the significant changes in mental health service organizations over the years, including the various new teams devised and the importance of central planning and targets. The authors Tom Burns and Mike Firn are pioneers in this field of research and are active in community outreach as practitioners, researchers, and supervisors. In 29 chapters they cover key discussions in conceptual issues, health and social care practice, management and development, which provides readers with an insight into the reality of community outreach work.
