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Seasonal Climate: Forecasting and Managing Risk
Originally formed around a set of lectures presented at a NATO Advanced Study Institute (ASI), this book has grown to become organised and presented rather more as a textbook than as a standard "collection of proceedings". This therefore is the first unified reference ‘textbook’ in seasonal to interannual climate predictions and their practical uses. Written by some of the world’s leading experts, the book covers a rapidly-developing science of prime social concern.
Hot Topics in Cell Biology
Summary This book is a definitive overview of the current 'state of the art' in cell biology. It is based on papers presented by leading researchers at the Spanish Society for Cell Biology's XIV Congress - a Congress that strives to achieve scientific excellence. Each participant was asked to prepare a 'mini review' of current and likely future development in their area of research. This book is based on those reviews. As such, it is therefore an analysis of current and future trends. Key Features Contains contributions from some of the world's leading researchers. The book is multidisciplinary, covering almost all topics in cell biology: from basic to applied cell biology, and a wide variet...
Neuroepigenomics in Aging and Disease
Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan:...
Hydrological, Socioeconomic and Ecological Impacts of the North Atlantic Oscillation in the Mediterranean Region
The Mediterranean basin represents one of the most important “hot spots” of climate change in the world, with recent trends towards a hotter and drier climate being related to changes in atmospheric circulation patterns. Such changes can have significant impacts in the climate of this region but also on the natural environment and several socioeconomic activities. Among these patterns, the North Atlantic Oscillation (NAO) is one of the main forcing factors in the region with impact on extreme events such as droughts, severe precipitations or heat and cold waves, the availability of water resources, the ecological dynamics, the quality and quantity of crops, the migration and welfare of a...
Trends in Artificial Intelligence and Computer Engineering
This book constitutes the proceedings of the 3rd International Conference on Advances in Emerging Trends and Technologies (ICAETT 2021), held in Riobamba, Ecuador, on November 10–12, 2021, proudly organized by Facultad de Informática y Electrónica (FIE) at Escuela Superior Politécnica de Chimborazo and supported by GDEON. ICAETT 2021 brings together top researchers and practitioners working in different domains of computer science to share their expertise and to discuss future developments and potential collaborations. Presenting high-quality, peer-reviewed papers, the book discusses the following topic e-Business e-Learning Intelligent systems Machine vision Security Technology trends
The Climate of the Mediterranean Region
The Mediterranean region contains a diverse and interesting climate ranging from areas with permanent glaciers to areas of subtropical, semiarid regions. The region is potentially sensitive to climate change and its progress has environmental, social, and economic implications within and beyond the region. Produced by the Mediterranean Climate Variability and Predictability Research Networking Project, this book reviews the evolution of the Mediterranean climate over the past two millennia with projections further into the twenty-first century as well as examining in detail various aspects of the Mediterranean region's climate including evolution, atmospheric variables, and oceanic and land ...
Olives and Olive Oil in Health and Disease Prevention
Long used in sacred ceremonies and associated with good health, the nutritional and health promoting benefits of olives and olive oils have been proven by an ever-increasing body of science. From cardiovascular benefits to anti-microbial, anti-cancer, antioxidant activity and effects on macrophages and aptoptosis to cellular and pathophysiollogical process, olives and olive oils are proving important in many healthful ways. For example, reactive components in olive oils or olive oil by-products have now been isolated and identified. These include tyrosol, hydroxytyrosol, 3,4-dihydroxyphenyl acetic acid elenolic acid and oleuropein. Oleic acid is the main monosaturated fatty acid of olive oil...
Electric Distribution Network Planning
This book highlights the latest research advances in the planning and management of electric distribution networks. It addresses various aspects of distribution network management including planning, operation, customer engagement, and technology accommodation. Given the importance of electric distribution networks in power delivery systems, effectively planning and managing them are vital to satisfying technical, economic, and customer requirements. A new planning and management philosophy, techniques, and methods are essential to handling uncertainties associated with the integration of renewable-based distributed generation, demand forecast, and customer needs. This book covers topics on managing the capacity of distribution networks, while also addressing the future needs of electric systems. The efficient and economical operation of distribution networks is an essential aspect of ensuring the effective use of resources. Accordingly, this book addresses operation and control approaches and techniques suitable for future distribution networks.
Advances in Usability, User Experience, Wearable and Assistive Technology
This book addresses emerging issues in usability, interface design, human–computer interaction, user experience and assistive technology. It highlights research aimed at understanding human interactions with products, services and systems and focuses on finding effective approaches for improving the user experience. It also discusses key issues in designing and providing assistive devices and services for individuals with disabilities or impairment, offering them support with mobility, communication, positioning, environmental control and daily living. The book covers modeling as well as innovative design concepts, with a special emphasis on user-centered design, and design for specific po...
Towards New Therapies for Parkinson's Disease
Parkinson's disease (PD) is characterised clinically by various non-motor and progressive motor symptoms, pathologically by loss of dopamine producing cells and intraneuronal cytoplasmic inclusions composed primarily of ?-synuclein. By the time a patient first presents with symptoms of Parkinson's disease at the clinic, a significant proportion of the cells in the substantia nigra have already been destroyed. This degeneration progresses despite the current therapies until the cell loss is so great that the quality of normal life is compromised. The dopamine precursor levodopa is the most valuable drug currently available for the treatment of PD. However for most PD patients, the optimal clinical benefit from levodopa decreases around five to six years of treatment. The aim of the chapters of this book is to work towards an understanding in the mechanisms of degeneration and to develop disease modifying therapies.
