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An insightful, revealing history of the magical mathematics that transformed our world. The Lady Tasting Tea is not a book of dry facts and figures, but the history of great individuals who dared to look at the world in a new way. At a summer tea party in Cambridge, England, a guest states that tea poured into milk tastes different from milk poured into tea. Her notion is shouted down by the scientific minds of the group. But one man, Ronald Fisher, proposes to scientifically test the hypothesis. There is no better person to conduct such an experiment, for Fisher is a pioneer in the field of statistics. The Lady Tasting Tea spotlights not only Fisher's theories but also the revolutionary ide...
This book explains how the computer programs work and why and when they can be applied to problems in toxicology. It discusses the statistical models used and their applications in a general fashion. The book overviews the problems that can arise from the blind use of the statistical models.
We live in a world that is not quite "right." The central tenet of statistical inquiry is that Observation = Truth + Error because even the most careful of scientific investigations have always been bedeviled by uncertainty. Our attempts to measure things are plagued with small errors. Our attempts to understand our world are blocked by blunders. And, unfortunately, in some cases, people have been known to lie. In this long-awaited follow-up to his well-regarded bestseller, The Lady Tasting Tea, David Salsburg opens a door to the amazing widespread use of statistical methods by looking at historical examples of errors, blunders and lies from areas as diverse as archeology, law, economics, me...
This thought-provoking book discusses the use of statistics in randomized clinical trials. Its aim is two-fold: firstly, it presents a clear account of the design and analysis of experiments in this setting which stresses the foundational issues involved. Secondly, the book seeks to develop the specific tools of analysis which can be derived from Neyman's model of restricted tests. The book is based on the author's many years of experience of clinical trials. Throughout, examples are used from a variety of types of study. As a result, all statisticians and research scientists who work on clinical trials will find this presentation clear and accessible, and very relevant to their own research interests.
The beauty of DOE is about learning--from mistakes, from trying new things, and from working with others. Cautionary Tales in Designed Experiments aims to explain statistical design of experiments (DOE), Ronald Fisher's great innovation, to readers with minimal mathematical knowledge and skills. The book starts with historical examples and goes on to cover missteps, mismanaged experiments, learnings, the importance of randomization, and more. In later chapters, the book covers more statistical concepts, such as various designs for experiments, analysis of variance, Bayes' theorem in DOE, measurement, and when experiments fail. The book concludes by citing the ubiquity of statistical design of experiments.
An innocent young country maiden is sold by her family into the harem of a ruthless king. Here is the story behind the Biblical book, The Song of Songs. The king is said to have 700 wives and 300 concubines, 40,000 chariots, and is the author of 3,000 proverbs. Can the maiden find love in his House of Women among the petty jealousies of his bitter wives?
A daily glass of wine prolongs life—yet alcohol can cause life-threatening cancer. Some say raising the minimum wage will decrease inequality while others say it increases unemployment. Scientists once confidently claimed that hormone replacement therapy reduced the risk of heart disease but now they equally confidently claim it raises that risk. What should we make of this endless barrage of conflicting claims? Observation and Experiment is an introduction to causal inference by one of the field’s leading scholars. An award-winning professor at Wharton, Paul Rosenbaum explains key concepts and methods through lively examples that make abstract principles accessible. He draws his example...
This collection of papers on aspects of statistics in toxicology is will be of interest to all medical statisticians. It offers findings from numerous leading experts from around the world including A. Whitehead and R. N. Connor (University of Reading), L. Ryan (Harvard), A. P. Grieve (Pfizer Research), K.J. Risko (Northern Telecom), and B.H. Margolin (University of North Carolina). This is the latest in the popular Royal Statistical Society Lecture Series, and will be essential reading for all those involved in this area.
Scientific progress depends on good research, and good research needs good statistics. But statistical analysis is tricky to get right, even for the best and brightest of us. You'd be surprised how many scientists are doing it wrong. Statistics Done Wrong is a pithy, essential guide to statistical blunders in modern science that will show you how to keep your research blunder-free. You'll examine embarrassing errors and omissions in recent research, learn about the misconceptions and scientific politics that allow these mistakes to happen, and begin your quest to reform the way you and your peers do statistics. You'll find advice on: –Asking the right question, designing the right experime...
This book is tailored for the countless individuals entrusted with driving improvement initiatives within their businesses or organizations. This diverse group includes leaders spanning from CEOs to front-line employees. Their responsibilities include a wide spectrum, from formulating and executing strategic plans to seizing incremental improvement opportunities. Within these pages, you will uncover the essential elements necessary for effectively implementing and sustaining improvement efforts across any organizational context. The authors distill years of experience, research, and analysis into five key concepts. These Five Keys empower practitioners to lead with confidence, bridging the gap between common sense and practical application.