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Computational biology is a rapidly expanding field, and the number and variety of computational methods used for DNA and protein sequence analysis is growing every day. These algorithms are extremely valuable to biotechnology companies and to researchers and teachers in universities. This book explains the latest computer technology for analyzing DNA, RNA, and protein sequences. Clear and easy to follow, designed specifically for the non-computer scientist, it will help biologists make better choices on which algorithm to use. New techniques and demonstrations are elucidated, as are state-of-the-art problems, and more advanced material on the latest algorithms. The primary audience for this ...
This book constitutes the refereed proceedings of the 10th International Colloquium on Grammatical Inference, ICGI 2010, held in Valencia, Spain, in September 2010. The 18 revised full papers and 14 revised short papers presented were carefully reviewed and selected from numerous submissions. The topics of the papers presented vary from theoretical results about the learning of different formal language classes (regular, context-free, context-sensitive, etc.) to application papers on bioinformatics, language modelling or software engineering. Furthermore there are two invited papers on the topics grammatical inference and games and molecules, languages, and automata.
A collection of articles by leading experts in theoretical computer science, this volume commemorates the 75th birthday of Professor Rani Siromoney, one of the pioneers in the field in India. The articles span the vast range of areas that Professor Siromoney has worked in or influenced, including grammar systems, picture languages and new models of computation.
In the 150 years since Darwin, evolutionary biology has proven as essential as it is controversial, a critical concept for answering questions about everything from the genetic code and the structure of cells to the reproduction, development, and migration of animal and plant life. But today, as David P. Mindell makes undeniably clear in The Evolving World, evolutionary biology is much more than an explanatory concept. It is indispensable to the world we live in. This book provides the first truly accessible and balanced account of how evolution has become a tool with applications that are thoroughly integrated, and deeply useful, in our everyday lives and our societies, often in ways that w...
This book constitutes the strictly refereed post-workshop proceedings of the German Conference on Bioinformatics, GCB'96, held in Leipzig, Germany, in September/October 1996. The volume presents 18 revised full papers together with three invited papers; these contributions were selected after a second round of reviewing from the 91 conference presentations. The book addresses current issues in computational biology and biologically inspired computing. The papers are organized in sections on biological and metabolic pathways, sequence analysis, molecular modeling, visualization, and formal languages, and DNA.
Genome research will certainly be one of the most important and exciting sci- tific disciplines of the 21st century. Deciphering the structure of the human genome, as well as that of several model organisms, is the key to our understanding how genes fu- tion in health and disease. With the combined development of innovativetools, resources, scientific know-how, and an overall functional genomic strategy, the origins of human and other organisms’geneticdiseases can be traced. Scientificresearch groups and dev- opmental departments of several major pharmaceutical and biotechnological companies are using new, innovative strategies to unravel how genes function, elucidating the gene protein pr...
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The application ofcomputational methods to solve scientific and practical problems in genome research created a new interdisciplinary area that transcends boundaries tradi tionally separating genetics, biology, mathematics, physics, and computer science. Com puters have, of course, been intensively used in the field of life sciences for many years, even before genome research started, to store and analyze DNA or protein sequences; to explore and model the three-dimensional structure, the dynamics, and the function of biopolymers; to compute genetic linkage or evolutionary processes; and more. The rapid development of new molecular and genetic technologies, combined with ambitious goals to ex...
A guide to machine learning approaches and their application to the analysis of biological data. An unprecedented wealth of data is being generated by genome sequencing projects and other experimental efforts to determine the structure and function of biological molecules. The demands and opportunities for interpreting these data are expanding rapidly. Bioinformatics is the development and application of computer methods for management, analysis, interpretation, and prediction, as well as for the design of experiments. Machine learning approaches (e.g., neural networks, hidden Markov models, and belief networks) are ideally suited for areas where there is a lot of data but little theory, whi...
This book constitutes the thoroughly refereed post-proceedings of the First VLDB 2006 International Workshop on Data Mining and Bioinformatics, VDMB 2006, held in Seoul, Korea in September 2006 in conjunction with VLDB 2006. The 15 revised full papers cover various topics in the areas of microarray data analysis, bioinformatics system and text retrieval, application of gene expression data, and sequence analysis.