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Mathematical Approaches to Biomolecular Structure and Dynamics
This IMA Volume in Mathematics and its Applications MATHEMATICAL APPROACHES TO BIOMOLECULAR STRUCTURE AND DYNAMICS is one of the two volumes based on the proceedings of the 1994 IMA Sum mer Program on "Molecular Biology" and comprises Weeks 3 and 4 of the four-week program. Weeks 1 and 2 appeared as Volume 81: Genetic Mapping and DNA Sequencing. We thank Jill P. Mesirov, Klaus Schulten, and De Witt Sumners for organizing Weeks 3 and 4 of the workshop and for editing the proceedings. We also take this opportunity to thank the National Institutes of Health (NIH) (National Center for Human Genome Research), the National Science Foundation (NSF) (Biological Instrumen tation and Resources), and t...
New Scientific Applications of Geometry and Topology
Geometry and topology are subjects generally considered to be "pure" mathematics. Recently, however, some of the methods and results in these two areas have found new utility in both wet-lab science (biology and chemistry) and theoretical physics. Conversely, science is influencing mathematics, from posing questions that call for the construction of mathematical models to exporting theoretical methods of attack on long-standing problems of mathematical interest. Based on an AMS Short Course held in January 1992, this book contains six introductory articles on these intriguing new connections. There are articles by a chemist and a biologist about mathematics, and four articles by mathematicians writing about science and mathematics involved. Because this book communicates the excitement and utility of mathematics research at an elementary level, it is an excellent textbook in an advanced undergraduate mathematics course.
Lectures on Topological Fluid Mechanics
Helmholtz's seminal paper on vortex motion (1858) marks the beginning of what is now called topological fluid mechanics.After 150 years of work, the field has grown considerably. In the last several decades unexpected developments have given topological fluid mechanics new impetus, benefiting from the impressive progress in knot theory and geometric topology on the one hand, and in mathematical and computational fluid dynamics on the other. This volume contains a wide-ranging collection of up-to-date, valuable research papers written by some of the most eminent experts in the field. Topics range from fundamental aspects of mathematical fluid mechanics, including topological vortex dynamics and magnetohydrodynamics, integrability issues, Hamiltonian structures and singularity formation, to DNA tangles and knotted DNAs in sedimentation. A substantial introductory chapter on knots and links, covering elements of modern braid theory and knot polynomials, as well as more advanced topics in knot classification, provides an invaluable addition to this material.
Mathematics of DNA Structure, Function and Interactions
Propelled by the success of the sequencing of the human and many related genomes, molecular and cellular biology has delivered significant scientific breakthroughs. Mathematics (broadly defined) continues to play a major role in this effort, helping to discover the secrets of life by working collaboratively with bench biologists, chemists and physicists. Because of its outstanding record of interdisciplinary research and training, the IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. The kickoff event for this thematic year was a tutorial on Mathematics of Nucleic Acids, followed by the workshop Mathematics of Molecular and Cellular ...
Topology and Geometry in Polymer Science
This IMA Volume in Mathematics and its Applications TOPOLOGY AND GEOMETRY IN POLYMER SCIENCE is based on the proceedings of a very successful one-week workshop with the same title. This workshop was an integral part of the 1995-1996 IMA program on "Mathematical Methods in Materials Science." We would like to thank Stuart G. Whittington, De Witt Sumners, and Timothy Lodge for their excellent work as organizers of the meeting and for editing the proceedings. We also take this opportunity to thank the National Science Foun dation (NSF), the Army Research Office (ARO) and the Office of Naval Research (ONR), whose financial support made the workshop possible. A vner Friedman Robert Gulliver v PREFACE This book is the product of a workshop on Topology and Geometry of Polymers, held at the IMA in June 1996. The workshop brought together topologists, combinatorialists, theoretical physicists and polymer scientists, who share an interest in characterizing and predicting the microscopic en tanglement properties of polymers, and their effect on macroscopic physical properties.
Random Knotting and Linking
This volume includes both rigorous asymptotic results on the inevitability of random knotting and linking, and Monte Carlo simulations of knot probability at small lengths. The statistical mechanics and topology of surfaces on the d-dimensional simple cubic lattice are investigated. The energy of knots is studied both analytically and numerically. Vassiliev invariants are investigated and used in random knot simulations. A mutation scheme which leaves the Jones polynomial unaltered is described. Applications include the investigation of RNA secondary structure using Vassiliev invariants, and the direct experimental measurement of DNA knot probability as a function of salt concentration in random cyclization experiments on linear DNA molecules. The papers in this volume reflect the diversity of interest across science and mathematics in this subject, from topology to statistical mechanics to theoretical chemistry to wet-lab molecular biology.
New Scientific Applications of Geometry and Topology
Geometry and topology are subjects generally considered to be pure mathematics. However, some of the methods and results in these two areas have found uses in both wet-lab science (biology and chemistry) and theoretical physics. Conversely, science is influencing mathematics, from posing questions that call for the construction of mathematical models to exporting theoretical methods of attack on long-standing problems of mathematical interest. Based on an AMS Short Course held in January 1992, this book contains six introductory articles on these intriguing connections. There are articles by a chemist and a biologist about mathematics, and four articles by mathematicians writing about science and mathematics involved. Because this collection communicates the utility of mathematics research at an elementary level, it should be a useful textbook for an advanced undergraduate mathematics course.
Lectures on Topological Fluid Mechanics
This volume contains a wide-ranging collection of valuable research papers written by some of the most eminent experts in the field. Topics range from fundamental aspects of mathematical fluid mechanics to DNA tangles and knotted DNAs in sedimentation.
Applications of Knot Theory
Louis Kauffman discusses applications of knot theory to physics, Nadrian Seeman discusses how topology is used in DNA nanotechnology, and Jonathan Simon discusses the statistical and energetic properties of knots and their relation to molecular biology."--BOOK JACKET.
