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Research as Development
In Research as Development, Salla Sariola and Bob Simpson show how international collaboration operates in a setting that is typically portrayed as "resource-poor" and "scientifically lagging." Based on their long-term fieldwork in Sri Lanka, Sariola and Simpson bring into clear ethnographic focus the ways international scientific collaborations feature prominently in the pursuit of global health in which research operates "as" development and not merely "for" it. The authors follow the design, inception, and practice of two clinical trials: one a global health charity funded trial and the other a pharmaceutical industry-sponsored trial. Research as Development situates these two trials with...
Research Ethics in Epidemics and Pandemics
Zusammenfassung: This open access casebook addresses complex and important ethical challenges arising when health-related research in conducted in the context of epidemics and pandemics. This book provides contextually-rich real-world case studies illustrating research ethics issues encountered by researchers, ethics reviewers and regulators around the globe during the COVID-19 pandemic. The accompanying commentaries outline relevant conceptual approaches and ethical considerations. These promote understanding and reflection on relevant ethical issues, ethical approaches and competing considerations in a manner supporting thoughtful evaluation of their implications for practice. As such the casebook is relevant to academic and professional audiences with an interest in global health, research ethics, and outbreaks and epidemics
Socio-cultural Dimensions of Emerging Infectious Diseases in Africa
This volume examines the most important socio-cultural, political, economic, and policy issues related to emerging infectious diseases in Africa. The volume covers the work of the Global Emerging Pathogens Treatment Consortium (GET); it looks at the challenges of science education and communication in Africa, the global health and governance of pandemics and epidemics, and more. It looks beyond such threats as Ebola, SARS, and Zika to consider the ways communities have sought to contain these and other deadly pathogens. The chapters provide a better understanding of a global health problem from an African perspective, which help clarify to readers why some responses have worked while others have not. Overall, the volume captures the state of the art, science, preparedness, and evolution of a topic important to the health of Africa and the world. It has a broad appeal across disciplines, from medical science and biomedical research, through research ethics, regulation and governance, science and health communication, social sciences, and is also of interest to general readers.
Perinatal Programming
Perinatal factors are critical in the 'programming' of behavioral, endocrine and immunologic outcomes of adult life. Exposure to many factors in utero can drive fetal development along specific trajectories. Perinatal factors can also affect many diverse systems that have significant implications for long-term health outcomes. The findings from basic research are so diverse and suggest implications in many different arenas. Bringing together these findings, this book explores the evidence linking the role of early life events to long-term physical and psychological health outcomes. It pulls the research together and communicates the findings to the wider scientific and clinical communities.
Biodemography
An authoritative overview of the concepts and applications of biological demography This book provides a comprehensive introduction to biodemography, an exciting interdisciplinary field that unites the natural science of biology with the social science of human demography. Biodemography is an essential resource for demographers, epidemiologists, gerontologists, and health professionals as well as ecologists, population biologists, entomologists, and conservation biologists. This accessible and innovative book is also ideal for the classroom. James Carey and Deborah Roach cover everything from baseline demographic concepts to biodemographic applications, and present models and equations in di...
A Design Thinking, Systems Approach to Well-Being Within Education and Practice
The mental health and well-being of health professionals is a topic that is broad, exceptionally relevant, and urgent to address. It is both a local and a global issue, and affects professionals in all stages of their careers. To explore this topic, the Global Forum on Innovation in Health Professional Education held a 1.5 day workshop. This publication summarizes the presentations and discussions from the workshop.
Family matters
Family-based studies, including intergenerational, sibling, and twin studies, are increasingly being used to explore life course epidemiology. However, there are issues relating to study design and the statistical analysis of family-based studies that are still not well understood, and comprehending the underlying assumptions of these studies and drawing the inferences from them can be complex. This book provides the knowledge and skills required to design, analyse, and correctly interpret family-based studies. It explains what these studies can tell us about life course epidemiology; provides practical guidance on how to set-up and maintain birth cohorts for completing family-based studies ...
Gene Expression and Its Discontents
Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner. Taking classic results on spontaneous symmetry breaking abducted from statistical physics in groupoid, rather than group, circumstances, the work suggests that epigenetic information sources act as analogs to a tunable catalyst, directing development into different characteristic pathways according to the structure of external signals. The results have significant implications for epigenetic epidemiology, in particular for understanding how environmental stressors, in a large sense, can induce a broad spectrum of developmental disorders in humans. The authors then apply the perspective to a number of chronic diseases broadly associated with obesity, using data at different scales of observation.
