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A "questão do Oriente" vem atravessando o marxismo em toda a sua trajetória histórica. Seja em sua dimensão teórica, já aberta com Marx e de que Gramsci fez a matéria de uma elaboração original, seja em sua dimensão política, com a eclosão das revoluções soviética e chinesa, que escreveram a história do século XX e que continuam a inspirar, em grandemedida, as lutas de emancipação social. Questão que continua a nos interrogar hoje, nos conflitos, lutas e nas contradições sociais, nacionais e religiosas de nossa contemporaneidade. Marxismo e Oriente: quando as periferias tornam-se os centros constitui-se em um esforço por todos os títulos admirável de estabelecer os nexos do marxismo com o Oriente, em suas tantas facetas, reconstruindo com rigor analítico a trama sutil que as recobre e levando-nos, ao percorrer as páginas deste livro, a revisitar essas relações complexas e tortuosas, em seus impasses e em suas possibilidades libertadoras, em seus aspectos conceituais e políticos.
Electromagnetic Environments and Health in Buildings brings together the work of an international group of specialists in this fragmented subject area. The book covers health effects of electromagnetic fields, emission standards and offers some
Quantitative Structure-Activity Relationships (QSARs) are increasingly used to predict the harmful effects of chemicals to humans and the environment. The increased use of these methods in a variety of areas (academic, industrial, regulatory) results from a realization that very little toxicological or fate data is available on the vast amount of chemicals to which humans and the environment are exposed. Predicting Chemical Toxicity and Fate provides a comprehensive explanation of the state-of-the-art methods that are available to predict the effects of chemicals on humans and the environment. It describes the use of predictive methods to estimate the physiochemical properties, biological ac...
This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage includes the basic mechanisms involved in hormone pulsatility, the significance of pulsatility in normal and disease conditions, the relevance of circadian rhythms, changes with ageing, and detailed consideration of specific peptide hormone systems. This book includes contributions from professionals working in both basic and clinical research and reveals much new and exciting work in this area and promises new research directions.
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With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of the current state-of-the-art in mitochondrial research. The book opens with the regulation of mitochondrial replication and biogenesis and reviews the mechanisms and functional consequences of mitochondrial fission and fusion. Further chapters address mitochondria and oxidative stress and their roles in cell signalling and cell death. The book includes extensive, fascinating discussion of the biochemistry of mitochondrial cell signalling (especially involving calcium) and of oxidative stress. The nature of the proteins engaged in these process...
Pathobiochemistry means biochemistry of disease. In the curriculum of medical studies it may serve as a useful and highly enjoyable “bridge” between the basic science of the first years, and the clinical training later. Practical limitations dictate that from a vast area of human pathology a careful selection of topics must be made. The eleven chapters of this book deal with the basics of acid-base balance disorders, inflammation, reactive oxygen species and antioxidant defense, non-enzymatic glycations, atherosclerosis, metabolic syndrome, ischemia/reperfusion of the heart, protein misfolding disorders, ageing, and consequences of alcohol abuse. The selection covers some pathogenetic processes behind several important medical problems of the present. Further, it more or less implicitly points to the inner causes of diseases. The inner maintenance of body structural and chemical integrity is costly and has its limits that regularly get exceeded, which is the ultimate reason for ageing and contributes to many, often also age-related, civilization diseases.
This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It covers the structure, function and regulation of mammalian TRP channels and mechanisms of signal transduction. The discussions indicate research that would improve understanding of the role of TRP channels in normal cellular physiology, the involvement of TRP channels in disease states and their potential use as molecular targets for novel therapeutic agents.