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Optimizing the "Drug-Like" Properties of Leads in Drug Discovery
This book arises from a workshop organized by the American Association of Pharmaceutical Scientists entitled "Optimizing the Drug-Like Properties of Leads in Drug Discovery," which took place in Parsippany, NJ in September 2004. The workshop focused on the optimization of the drug-like properties of leads in drug discovery. The volume outlines strategies and methodologies designed to guide pharmaceutical and biotechnology companies through the drug discovery and development process.
Pharmaceutical Profiling in Drug Discovery for Lead Selection
At a time when pharmaceutical companies have limited resources to develop newer and better drugs, they must continually evaluate the effectiveness and efficiency of their research and development process. This volume focuses on how to increase the efficiency of drug discovery and development. Written by experienced discovery scientists from diverse disciplines, including chemistry, drug metabolism, and development sciences, it details in silico, in vitro, and in vivo tools for prediction, measurement, and application of compound properties to select and improve potential drug candidates.
Enzyme- and Transporter-Based Drug-Drug Interactions
Germination of the thought of "Enzymatic- and Transporter-Based Drug-Drug Interactions: Progress and Future Challenges" Proceedings came about as part of the annual meeting of The American Association of Pharmaceutical Scientists (AAPS) that was held in San Diego in November of 2007. The attendance of workshop by more than 250 pharmaceutical scientists reflected the increased interest in the area of drug-drug interactions (DDIs), the greater focus of PhRMA, academia, and regulatory agencies, and the rapid pace of growth in knowledge. One of the aims of the workshop was to address the progress made in quantitatively predicting enzyme- and transporter-based DDIs as well as highlighted areas wh...
Published Scientific Papers of the National Institutes of Health
Each issue lists papers published during the preceding year.
Indian Cotton Annual
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Trust Management VI
This book constitutes the refereed proceedings of the 6th IFIP WG 11.11 International Conference, IFIPTM 2012, held in Surat, India, in May 2012. The 12 revised full papers presented together with 8 short papers and the abstracts of 4 keynote talks were carefully reviewed and selected from 51 submissions. Building on the traditions inherited from the iTrust and previous IFIPTM conferences, IFIPTM 2012 is a multi-disciplinary conference focusing on areas such as: trust models, social, economic and behavioural aspects of trust, trust in networks, mobile systems and cloud computation, privacy, reputation systems, and identity management.
Chemical Biology
An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry ...
