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Topic Editor Dr. MacLeod is employed by Janssen. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
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This open access book is written by world-renowned experts on radiomolecular precision oncology to celebrate the work, life, principles and ideology of Richard P Baum. It includes commentaries, reviews and some thought provoking novel ideas on radionuclide precision oncology, covering topics such as various aspects of theranostics and molecular radiotherapy like radiolabeled peptides, radiolabeled antibodies, dosimetry, and quality control as well as the diagnosis and treatment of specific tumor types. Featuring contributions by biologists, physicists, chemists, mathematicians, geneticists, and physicians from a range of specialties, this Festschrift is highly interdisciplinary and will be a valuable resource for future precision oncologists.
This book covers scientific, clinical, and educational aspects of radiotheranostics in cancer control. Setting the framework, the first volume defines radiotheranostics and describes the history of radionuclide therapy and theranostics, and the biology of cancer. It examines the clinical applications of unconjugated radionuclides, such as 131I and 223Ra, and of radionuclide-conjugated cancer-specific vectors: peptides, small molecules, antibodies, and nanoparticles; introduces clinical trials and drug development; and reviews epidemiological studies and the adverse effects of radionuclide therapy – both radiation injuries and chemical toxicity. It presents the chemistry and physics of radi...
Using SWOT analysis, this book examines in detail the strengths and weaknesses of the hybrid modalities PET-CT and PET-MRI for imaging of the central nervous system, comparing their merits and evaluating their advantages over the stand-alone modalities. The aim is to employ a truly systematic approach in order to define the potential clinical benefit of these modalities and to identify shortcomings, opportunities, and threats. Clinical application of the modalities is explored in a range of conditions, including dementia and related disorders, movement disorders, psychiatric disorders, cerebrovascular disease, infection/inflammation, brain tumors, and pediatric neurologic disorders. In addition, the basics of hybrid imaging are addressed, covering physics, instrumentation, data analysis and quantitation, radiopharmaceuticals, and contrast media. PET-CT and PET-MRI in Neurology, written by experts from Europe and the United States, will be essential reading for imaging specialists and of value for neurologists, psychiatrists, neurosurgeons, and pediatricians.
The British Nuclear Medicine Society celebrates its 50th Anniversary with this booklet, which reflects the research of many of the pioneers in the use of radionuclides for the diagnosis and therapy of human disease. Since 1949 there have been remarkable advances in radionuclide techniques and imaging equipment: from the first devices “home-made” in the many physics departments throughout the UK, to the sophisticated multimodality imagers now in everyday use in Nuclear Medicine. The BNMS has been instrumental in promoting the use of radionuclide techniques in the investigation of pathology by supporting and providing education, research and guidelines on the optimum use of radiation to help patients. The future of Nuclear Medicine is bright, thanks to improved imaging resolution, new radiopharmaceuticals, and new diagnostic and therapeutic techniques and procedures.
Cancer is a global burden with more than 18 million diagnosed and an estimate of 10 million deaths in 2020 worldwide. Cancer continues to be a major and growing problem in conflict affected areas too. The incidence of cancer is expected to rise significantly in those countries compared to the rest of the world. Conflict, massive migration and displacement has put a tremendous pressure on all health care systems and health economy which halted improvement in many cancer care in majority of the countries. Countries affected by conflict like Syria, Ukraine, Iraq, Yemen, Latin America and others has led to destruction of the whole countries healthcare infrastructure including health care facilit...
This open access book will provide a foundation for the understanding of, and knowledge for a successful routine use of diagnostic Nuclear Medicine procedures in children through expertise and cases provided by representative busy pediatric nuclear medicine facilities. The book highlights important aspects of nuclear medicine in children and the differences between adult and pediatric practice where relevant. An introductory chapter provides general information detailing the advantages and limitations for performing nuclear medicine tests in children, as well as suggestions on how to approach and provide relevant data to the patients, their parents or next of kin. In the remaining 11 chapter...
Nuclear Cardiac Imaging is the definitive resource for nuclear cardiologists and nuclear clinicians on the technical, physiological, diagnostic, and prognostic considerations of cardiac diagnostic techniques performed with the aid of radiopharmaceuticals. New to the sixth edition are additional updated chapters and a Companion Atlas featuring case studies and multiple-choice quizzes that offer readers extra review.