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Holoscopy is a new tomographic imaging modality that combines techniques of digital holography with Fourier-domain optical coherence tomography (FD-OCT). Dierck Hillmann gives a theoretical introduction to the mathematics and physics of holoscopy and develops an efficient numerical reconstruction procedure. Compared to FD-OCT, holoscopy provides unique advantages by enabling tomographic imaging without a limited depth of focus, but results in an increased numerical cost for reconstruction. In further chapters, the author introduces techniques for FD-OCT that are relevant to holoscopy as well. He demonstrates and compares numerical reconstruction methods for FD-OCT and shows how motion and dispersion artifacts in FD-OCT can be numerically compensated.
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthal...
Defense of Scientific Hypothesis: From Reproducibility Crisis to Big Data argues that the scientific hypothesis is the key to understanding what science is about, and explains its importance for scientists and non-scientists alike. Most scientists, like the general public, receive only cursory formal instruction about the scientific hypothesis. Since we all constantly assess what's going on around us, we continually formulate and test hypotheses, consciously and unconsciously. The book distinguishes scientific from statistical hypotheses, analyzes the benefits of hypotheses and hypothesis testing, sorts out sciences that do not require hypotheses, discusses educational and social policies relating to the hypothesis, and offers advice on recognizing and formulating hypotheses.