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Drugs for Relapse Prevention of Alcoholism
Alcoholism is a pathological behavioural syndrome, characterised by comp- sive alcohol use, craving and relapses, even recurring after many years of abstinence. It is suggested that chronic alcohol abuse leads to persistent changes within several neurochemical pathways in the brain and furthermore that an imprinted drug and addiction memory may scarcely be extinguished. Hence, the question arises as to whether there ought to be a reasonable hope that pharmacological drugs will be developed that interfere with an addiction memory, and as a result, finally lead to a cure? In this book, leading preclinical and clinical experts in the field of alcohol relapse prevention strive to furnish an answ...
Basic and Clinical Science of Opioid Addiction
For the first time reports on methadone and heroin maintenance treatment with respect to clinical practice, research, methodological aspects, neuroscience and psychotherapy are brought together in this volume. They arise from a conference held in November 2001 in Basel. The Swiss approach of a highly structured outpatient treatment using methadone, heroin, morphine etc. to keep patients in treatment is discussed. Data of follow-up after heroin-assisted treatment is shown. Also a critical discussion of the history of treatment modalities and its scientific evaluation is presented. Further important topics such as brain imaging, opioid withdrawal, risks of treatment, and basic neurochemical research are presented. The issue concludes with the narrative experience of a practicing psychotherapist. This topical and outstanding overview gives psychiatrists, psychologists and psychotherapists, neuroscientists, physicians as well as decision makers in public health, politicians, counselors and social workers an excellent insight into stimulating and scientific research.
Trips
Trips shows, using color illustrations, the latest research, and bleeding-edge cultural analogies, how the still-mysterious hallucinogens may work in the still-mysterious brain. Written in language a general audience can understand, the book's tone is light and irreverent, yet at the same time deals with the drug culture in a serious way. Trips offers readers a rare look at the social, cultural, historical, and scientific phenomenon of psychedelics-through the eyes of artists who've grown up with them, regulators who control them, federal scientists who approve and fund their research, and scientists who've spent careers studying them—and in the process fills a growing need for truthful in...
Contribution to the Sensible Use of Benzodiazepines
Benzodiazepines are psychotropic drugs used to treat a variety of disorders including anxiety, panic attacks, insomnia and muscle spasm. An inter-governmental meeting of policy-makers and health experts in Europe was held in January 2001 to discuss a variety of issues relating to their use including: the level of consumption, both legally prescribed and through illegal use; risks of abuse and dependence; the regulatory situation and drug control measures. The text of a draft resolution adopted by the meeting on the appropriate use of benzodiazepines is also contained in the document.
The Brain-Behavioral Connection in Substance Use Disorders and Effects Associated with Injectable Opioid Prescription
The conception of substance dependence as a complex brain disorder calls into question folk-psychological views on the voluntary control of behavior and challenges the popular theory of Cartesian dualism. Although brain abnormalities in substance dependence have long been suspected, only in recent years has research begun to more clearly delineate brain alterations, correlating with measurable changes in behavior. However, no characteristic change has been found and the research findings are equivocal. On the other hand, the brain-behavioral connection in substance dependence offers insight into novel therapeutic approaches and helps to remove the pejorative undertone that often surrounds individuals with opioid or other substance dependence.
Drug Abuse
None
Current Catalog
First multi-year cumulation covers six years: 1965-70.
New and Upcoming Markers of Alcohol Consumption
Alcohol consumption in all European countries is one of the leading causes for productivity loss, premature death, and accidents and is a hazard to health. Therefore, in order to monitor alcohol consumption in clinical as well as in forensic practice, occupational medicine, at court and for traffic safety and safety at workplaces, biological state markers of high sensitivity and specificity, capable of monitoring those in treatment for alcohol dependence or poly-drug-abusers as well as social drinkers in risky situations (driving, workplaces) are required. The markers known today can not be considered satisfying with regard to these parameters. Therefore the aim of this book is to contribute to improving the above mentioned issues by promoting knowledge on new, by far more accurate, and both disease and time independent alcohol intake markers.
