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Safety Concerns for Herbal Drugs
Are herbal drugs totally devoid of adverse effects when used alone, as herbal formulations, or in concurrent use with modern medicines? Safety Concerns for Herbal Drugs examines that question and others like it to give you the information you need to judge for yourself the balance between the risks and benefits associated with the therapeutic use o
The Third Histamine Receptor
Reveals an Emerging Avenue of Potential Treatments for a Host of Challenging Diseases and Disorders The H3 receptor is known to play a major role in a range of CNS disorders, including those affecting cognitive functions such as ADHD and Alzheimer’s disease, as well as sleep disorders, obesity, epilepsy, schizophrenia, depression, and neurodegeneration. In light of dramatic advances in research at the molecular level, supported by impressive clinical studies, optimism remains high that an H3 receptor-related drug could hit the market soon. The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders provides a thorough grounding in advances made over the...
Adaptation under Stressful Environments through Biological Adjustments and Interventions
The book delves into the intricate interplay of stress and adaptive responses, and their multifaceted dynamics influenced by stress type, exposure duration, genetic factors, and lifestyle elements. It unveils the complexity of stress management, unveiling how adaptive strategies evolve in response to stressors. By harnessing scientific breakthroughs in stress response comprehension, the book navigates the path to effective stress mitigation. Through avenues such as pharmacological interventions, dietary adjustments, psychological enhancement, and more, the book advocates for achieving adaptive resilience—a state where the system effectively copes with stress. The text encapsulates an array of stressors, including extreme stress, oxidative stress, and genotoxic stress, dissecting their impact on systemic equilibrium and health. The book's focal point rests on adaptive mechanisms that vary with stressor types, while also spotlighting how these mechanisms can be calibrated through pharmacological and alternative means. This is an invaluable resource for understanding, mitigating, and harnessing the power of adaptation in the face of stress-induced challenges.
Experimental & Clinical Epilepsy and Related Comorbidities
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Proceedings of 12th International Conference and Exhibition on Pharmacovigilance & Drug Safety 2018
June 21-22, 2018 Rome, Italy Key Topics : Pre-Clinical and Clinical Trials, Adverse Drug Reactions, Pharmacovigilance and Risk Management, Good Pharmacovigilance Practice, Pharmacy Practices and its Challenges, Biopharmaceutical Sciences, Clinical Trials on Various Disorders, Data Quality Management and Analysis, Pharmacovigilance Significance & Scope, Diversity in Industrial Clinical Trials and Clinical Research, Clinical Research and Statistics, Case Report in Clinical Trials, Drug Safety, Clinical Data Base Management, PV Consultings and Business Opportunity, Regulatory Affairs, Entrepreneurs Investment Meet,
Herbal Medicine Applications for Polycystic Ovarian Syndrome
Polycystic ovarian syndrome (PCOS) is a multifaceted reproductive, metabolic syndrome, and its symptoms involve interactions between hormones, genes, and environmental stressors. The characteristic symptoms of PCOS include menstrual abnormalities such as oligomenorrhea or amenorrhea. The general symptoms of PCOS are anovulation or oligo-ovulation. Herbal Medicine Applications for Polycystic Ovarian Syndrome provides comprehensive information on different aspects of PCOS, including its pathogenesis, symptoms, therapies, and management, particularly through herbal remedies. With 13 chapters related to different aspects of PCOS, this book provides enormous knowledge about the pathogenesis and r...
Histamine in the brain
Brain aminergic pathways are organized in parallel and interacting systems, which support a range of functions, from homoeostatic regulations to cognitive, and motivational processes. Despite overlapping functional influences, dopamine, serotonin, noradrenaline and histamine systems provide different contributions to these processes. The histaminergic system, long ignored as a major regulator of the sleep-wake cycle, has now been fully acknowledged also as a major coordinator of attention, learning and memory, decision making. Although histaminergic neurons project widely to the whole brain, they are functionally heterogeneous, a feature which may provide the substrate for differential regul...
Signal Analysis in Pharmacovigilance
This book provides detailed concepts and information on principles and processes of signal analysis in pharmacovigilance along with case studies. It covers the fundamental concepts and principles of pharmacovigilance, emphasizing the need for robust signal detection and analysis methods. The book reviews the diverse array of databases and tools employed for signal detection, including electronic health records (EHRs), social media mining, claims data, and distributed data networks. In turn, the book discusses the application of molecular dynamics, molecular docking, and the use of the FDA Adverse Event Reporting System (FAERS) database in signal analysis. Toward the end, the book explores the identification, validation, and assessment of signals associated with vaccines. This book is useful for graduate, post-graduate students of pharmaceutical sciences, and scientists in pharmacology research and drug development.
