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AACR 2022 Proceedings: Part B April 11-13
The AACR Annual Meeting is the focal point of the cancer research community, where scientists, clinicians, other health care professionals, survivors, patients, and advocates gather to share the latest advances in cancer science and medicine. From population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy; the AACR Annual Meeting highlights the work of the best minds in cancer research from institutions all over the world.
Organelle and Molecular Targeting
We have surpassed the omics era and are truly in the Age of Molecular Therapeutics. The fast-paced development of SARS-CoV-2 vaccines, such as the mRNA vaccines encoding the viral spike protein, demonstrated the need for and capability of molecular therapy and nanotechnology-based solutions for drug delivery. In record speed, the SARS-CoV-2 viral RNA genome was sequenced and shared with the scientific community, allowing the rapid design of molecular therapeutics. The mRNA vaccines exploit the host cell endoplasmic reticulum to produce viral spike proteins for antigen presentation and recognition by the innate and adaptive immune system. Lipid nanoparticles enable the delivery of the fragile...
Immunity and Tolerance
The 78th Symposium volume covers many aspects of the immune system including the genetics, biochemistry, molecular and cell biology, and developmental biology of immune responses. New approaches intended to harness the immune system to treat disease, particularly cancer, are also discussed. The volume's broad synthesis of the current knowledge about immunity and tolerance includes molecular mechanisms of B and T lymphocyte development from the single cell to the entire organism and from single genes to genomes. There is a focus on the development and function of innate cells, including myeloid cells, natural killer cells, and a more recently defined innate lymphoid cell that resembles a T ce...
Die Stimme der Fremden
Nun gibt es eine Sonderausgabe – Dr. Norden Gold Dr. Norden ist die erfolgreichste Arztromanserie Deutschlands, und das schon seit Jahrzehnten. Mehr als 1.000 Romane wurden bereits geschrieben. Für Dr. Norden ist kein Mensch nur ein 'Fall', er sieht immer den ganzen Menschen in seinem Patienten. Er gibt nicht auf, wenn er auf schwierige Fälle stößt, bei denen kein sichtbarer Erfolg der Heilung zu erkennen ist. Immer an seiner Seite ist seine Frau Fee, selbst eine großartige Ärztin, die ihn mit feinem, häufig detektivischem Spürsinn unterstützt. Auf sie kann er sich immer verlassen, wenn es darum geht zu helfen. Die Pfingstferien hatten begonnen. Im Hause Norden waren die Koffer ge...
