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Postgraduate Haematology
"Most hematologists need a revised and practical textbook in whichthey can rapidly search on the morning of a consultation...Thisbook will be an important resource in suchsituations." New England Journal of Medicine A well established and respected review ofhematology Postgraduate Haematology is a practical, readable text whichwill give trainees, residents and practising hematologistsup-to-date knowledge of the pathogenesis, clinical and laboratoryfeatures and management of blood disorders. Postgraduate Haematology is ideal for: Trainees and residents in hematology Hematologists in practice Why Buy This Book? A well established and respected review ofhematology Practical and readable text Essential information for everyday use as well as thescientific background Up-to-date knowledge of the pathogenesis, clinical andlaboratory features and management of blood disorders Complete revision of all chapters and the addition of newchapters to reflect latest advances in the speciality
Disorders of Hemoglobin
Disorders of Hemoglobin stands tall as the definitive work on the genetics, pathophysiology, and clinical management of hemoglobinopathies and thalassemia. Drs. Steinberg, Forget, Higgs, and Nagel have gathered the world authorities on the science and clinical management of these disorders and created the authoritative textbook for researchers and clinicians alike.Authors describe the scientific basis of clinical features and provide clinicians with a clear background of disorders they treat and scientists with an essential link between their research and its clinical manifestation. Disorders of Hemoglobin is the only single-source reference on hemoglobinopathies for hematologists, pediatricians, clinical investigators, and geneticists worldwide.
Disorders of Hemoglobin
Completely revised new edition of the definitive reference on disorders of hemoglobin.
Hemoglobin Switching
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Regional Physical Mapping
Describes the detailed analysis of five regions of the human genome that have already been extensively characterized, such as a 4000-kb segment replete with genes that comprises the major histocompatibility complex, Xp21, and the terminal region of the short arm of chromosome 16. Annotation copyright by Book News, Inc., Portland, OR
Protides of the Biological Fluids
Protides of the Biological Fluids examines protides of the biological fluids and covers topics ranging from the use of DNA probes to diagnose inherited diseases and receptors to the conformation and function of biologically active peptides. This text has 115 chapters and begins by demonstrating the existence of gene families common to several vertebrates and which evolved by intragenic duplication. The chapters that follow focus on the use of DNA probes in the analysis of inherited disorders such as thalassemia and hemophilia. The reader is then introduced to receptors, especially for peptides. Receptors on circulating cells, hormone receptors, receptors involved in cancer, and immunoglobulin receptors are explored. The section on the conformation and function of biologically active peptides considers the methods including spectroscopic methods, crystallography, and theoretical conformational analysis. In particular, the use of synchrotron X-radiation in biological crystallography and of 2D NMR spectroscopy in the identification of folded structures in immunogenic peptides is highlighted. This book will be of value to biologists and biochemists.
Epigenetics, Environment, and Genes
Epigenetics refers to DNA and chromatin modifications that play an important role in the regulation of various genomic functions. This important book reviews human and cellular data that underline paradoxical findings with respect to the contribution of heredity and environment to phenotype. The contributors then reinterpret these experiments that incorporate epigenetic factors. Topics include DNA methylation, histone modifications, chromatin modifications, the role of epigenetic modifications and environment on gene expression, and integrating genomic medicine into clinical practice.
Long-Range Control of Gene Expression
Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. Discusses the evolution of cis-regulatory sequences in drosophila Includes information on genomic imprinting and imprinting defects in humans Includes a chapter on epigenetic gene regulation in cancer
