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Portuguese English Bilingual Bible The Torah
This is the Torah, volume one, of the Portuguese English Bilingual Bible book series. It is in English and Portuguese, two of the top ten most widely spoken languages on Earth. It is the King James Version and Almeida Recebida translations, good and accurate translations for learning either language, as well as having a correct and reliable translation from the received texts of the Holy Bible itself. The translators relied on "formal equivalence" to preserve phrasing and literal content from the Hebrew and Greek documents. This present volume is divided in columns for each language, with each corresponding verse line matching its equal on the opposite side of the page. The font size and style is easy to read. Typo's and the rare instance of missing information (such as superscriptions above psalms and colophons ending epistles) have been translated from English to Portuguese, and in some cases Hebrew into Portuguese, by Alan Lewis Silva, who has lovingly and carefully edited this wonderful book, the Torah.
Targeting Functional Centers of the Ribosome
This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself.
Biostimulants in Agriculture II: Towards a Sustainable Future
Modern agriculture needs to review and broaden its practices and business models, by integrating opportunities coming from different adjacent sectors and value chains, including the bio-based industry, in a fully circular economy strategy. Searching for new tools and technologies to increase crop productivity under optimal and sub-optimal conditions and to improve resources use efficiency is crucial to ensure food security while preserving soil quality, microbial biodiversity, and providing business opportunities for farmers. Biostimulants based on microorganisms or organic substances obtained from renewable materials represent a sustainable, efficient technology or complement to synthetic c...
Antibiotics
Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.
Soil Biology and Agriculture in the Tropics
The relationships between soils, microbes and humans are of crucial relevance in the tropics, where plant stress and microbial activity are exacerbated. This volume of Soil Biology presents the living component of tropical soils, showing how it is shaped by environmental conditions and emphasizing its dramatic impact on human survival and well-being. Following an introduction to the specificities of tropical soils and of their microbial communities, the biological aspects of soil management are examined, dealing with land use change, conservation and slash-and-burn agriculture, the restoration of hot deserts, agroforestry and paddy rice cultivation. As they are of particular relevance for tropical agriculture, symbioses of plants and microbes are thoroughly covered, as are the biodegradation of pesticides and health risks associated with wastewater irrigation. Lastly, traditional soil knowledge is discussed as a key to our sustainable presence in this world.
