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Pruritus
This book provides a thorough and comprehensive reference in the management of pruritus, designed to be a convenient resource for all physicians confronted with patients suffering from itch. The Editors have recruited a board of internationally renowned experts to provide an in-depth analysis of the causes and management of pruritus, including the current concepts in pathophysiology and novel therapeutics. Acute and chronic pruritus can represent significant management issues both as a common physiological sensation and as a manifestation of dermatologic and non-dermatologic diseases. All patients suffering from itch know that it is a very awkward sensation. Unfortunately, this often significant symptom is frequently considered less severe in comparison with pain. The consequences are that research on this field has been poorer than research on pain and that pruritus is therefore more difficult to treat. Pruritus, Second edition addresses the new concepts and discoveries that have modified our understanding of this condition. It explains the pathophysiology of itch, describes all causes, and provides guidelines for management and treatment.
Engineering Psychology and Cognitive Ergonomics
This book constitutes the refereed proceedings of the 9th International Conference on Engineering Psychology and Cognitive Ergonomics, EPCE 2011, held in Orlando, FL, USA, in July 2011, within the framework of the 14th International Conference on Human-Computer Interaction, HCII 2011, together with 11 other thematically similar conferences. The 67 full papers presented were carefully reviewed and selected from numerous submissions. The papers are organized in topical parts on cognitive and psychological aspects of interaction; cognitive aspects of driving; cognition and the Web; cognition and automation; security and safety; and aerospace and military applications.
Sensory Mechanisms of the Spinal Cord
As stated in the preface to the first edition, the goal of this monograph is to provide an overview of current thought about the spinal cord mechanisms responsible for sensory processing. We hope that the book will be of value to both basic neuroscientists and clinicians. The organization of the monograph has followed the original plan in most respects, although the emphasis has changed with respect to many topics because of recent advances. In particular, a substantial increase in the number of investigations of the dorsal root ganglion has led us to devote a chapter to this topic. The treatment of chemical neuroanatomy in the dorsal horn, as well as the relevant neuropharmacology, has also been expanded considerably. Another major emphasis is on the results of experiments employing microneurography in human subjects. We thank Margie Watson and Lyn Schilling for their assistance with the typing and Griselda Gonzales for preparing the illustrations.
Miscellaneous Series
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The Pottery Industry
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Itch
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease ...
Genomics and Clinical Medicine
An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.
Advances in Understanding Human Performance
Combining emerging concepts, theories, and applications of human factors knowledge, this volume focuses on discovery and understanding of human performance issues in complex systems, including recent advances in neural basis of human behavior at work (i.e. neuroergonomics), training, and universal design. The book is organized into ten sections tha
Pharmacology of Itch
Basic research on the pharmacology of itch has exploded in the wake of two very influential papers that were published in Nature (2007) and Science (2009). Long overlooked as a milder form of pain, itching has rapidly gained a new appreciation in both research and clinical communities because of its complexity and its negative effects on the quality of life of the distressed patients. Like pain, not all itches are the same. Unlike pain, there are no standard drugs equivalent to aspirin and morphine. Epidemiological studies emphasize the high incidence and economic costs of itch (pruritus). It is the most prevalent symptom of a wide variety of allergic and inflammatory skin conditions (e.g., ...
