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A controversial, wide ranging and clearly documented survey of the state of the global environment.
The present understanding of the various implications of lectins in pathology are summarised in this timely text. With contributions from leading investigators in the field of lectin research, Lectins and Pathology provides up-to-date information on key developments within this field, including the use of lectins and lectin-binding molecules as tools, the involvement of endogenous (animal or human) lectins in inflammation, cancer invasion and metastasis, as well as the importance of lectins in bacteriology and parasitology. This volume contains useful knowledge for clinical investigators, cell biologists, biochemists and biotechnologists, as well as for the graduate students interested in getting a comprehensive coverage of this field.
Lectins form a ubiquitous and important class of natural carbohydrate- binding information proteins. Although the main scientific interest was originally focussed on toxic lectins such as ricin, recent emphasis has shifted to exploring their involvement in cell-to-cell communication and recognition in microorganisms, plants and animals.; As knowledge of the basic properties and biological activities of lectins has increased, exciting opportunities have arisen for the exploitation of some of the advantageous aspects of fundamental lectinology.; "Lectins: Biomedical Perspectives" records the major achievements of an initiative, funded by the European Community, to coordinate lectin research throughout Europe.
Working from a multidisciplinary vantage point, this work reports on significant advances in the area of metabolic control, investigating theories that now include interacting enzymes, the concept of flux control, and the knowledge that single ``pacemaker'' enzymes are rarely found in metabolism. New methods are highlighted, such as the use of anti-idiotypic antibodies, electrophoresis in the presence of immobilized enzymes, and the use of molecular genetics in the study of metabolic regulation.