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Malaria Control and Elimination
This detailed book serves to provide a global overview of the goals, rationale, and scientific basis for malaria control and elimination, as well as tools, methods, and strategies to that end. Opening with a section on malaria epidemiology, the volume continues by covering tools that are critical to malaria management, anti-malarial drugs and resistance to these drugs, vaccination approaches against malaria, vector control, as well as some perspective on the future of the fight against this devastating disease. Written for the highly successful Method in Molecular Biology series, chapters in this collection feature the kind of practical, hands-on advice that leads to better results in the field. Authoritative and important, Malaria Control and Elimination is a valuable reference for all those involved in malaria control and elimination worldwide, from students to health practitioners and field researchers seeking to make eradication a reality wherever possible.
Perspectives of Stem Cells
Stem cells are fascinating cell types. They can replicate themselves forever while retaining the potential to generate progeny with speci?c functions. Because of these special properties, stem cells have been subjects of intensive investigation, from understanding basic mechanisms underlying tissue generation, to modeling human diseases, to application for cell replacement therapy. Stem cells come in different forms. For example, mouse embryonic stem cells can general all cell types in a body, either in a dish or when put back into mouse embryos. On the other hand, neural stem cells in the adult brain generate neurons and glia cells that contribute to the brain’s plasticity. Rapid progress...
Triumph of the Body
Following the Leonardo da Vinci exhibition, the Museum of Fine Arts hosts a show of Michelangelo?s drawings, the other genius of the Italian Renaissance. Drawing played a central role in the art of Michelangelo, who left behind an outstanding legacy mainly as a sculptor but also as a painter and architect. His drawings allow an insight into the creative process of the master?s celebrated works, since he prepared all his creations on paper. This exhibition catalogue is intended primarily for the general public. For this reason, the authors have refrained from debating the sophisticated questions of attribution regarding individual drawings, which are often difficult even for experts to unravel. Similarly, it was not their aim to discuss the uncertainties of dating specific works of art. Their objective was to set the drawings in the broader historical, social, political, or economic context of the period, and the main concern was to address the question of how the cult of Michelangelo, which still influences our judgement of his oeuvre, first manifested itself during his lifetime.00Exhibition: Museum of Fine Arts, Budapest, Hungary (06.04.-30.06.2019).
The Yeast Two-hybrid System
Biologists have already identified thousands of new gene sequences, and genome sequencing efforts are speeding up the discovery process even further. With this explosion of sequence information comes the need to understand how genes work in concert in order to fulfill the cells functions. The yeast two-hybrid system--used to identify protein-protein interactions--is one of the most powerful and versatile methods for characterizing a protein's function. It has become an essential tool for both academic researchers and those in biotechnology and pharmaceutical companies. This volume presents work by pioneers in the field and is the first publication devoted solely to the yeast two-hybrid syste...
Aldous Huxley Annual
Aldous Huxley Annual is the official organ of the Aldous Huxley Society at the Centre for Aldous Huxley Studies in Munster, Germany. It publishes essays on the life, times, and interests of Aldous Huxley and his circle. It aspires to be the sort of periodical that Huxley would have wanted to read and to which he might have contributed.
Biogenesis of Fatty Acids, Lipids and Membranes
Concise chapters, written by experts in the field, cover a wide spectrum of topics on lipid and membrane formation in microbes (Archaea, Bacteria, eukaryotic microbes).All cells are delimited by a lipid membrane, which provides a crucial boundary in any known form of life. Readers will discover significant chapters on microbial lipid-carrying biomolecules and lipid/membrane-associated structures and processes.
Minimal Cells: Design, Construction, Biotechnological Applications
This book provides a comprehensive overview of the design, generation and characterization of minimal cell systems. Written by leading experts, it presents an in-depth analysis of the current issues and challenges in the field, including recent advances in the generation and characterization of reduced-genome strains generated from model organisms with relevance in biotechnology, and basic research such as Escherichia coli, Corynebacterium glutamicum and yeast. It also discusses methodologies, such as bottom-up and top-down genome minimization strategies, as well as novel analytical and experimental approaches to characterize and generate minimal cells. Lastly, it presents the latest researc...
Evaluation of Enzyme Inhibitors in Drug Discovery
Vital information for discovering and optimizing new drugs "Understanding the data and the experimental details that support it has always been at the heart of good science and the assumption challenging process that leads from good science to drug discovery. This book helps medicinal chemists and pharmacologists to do exactly that in the realm of enzyme inhibitors." -Paul S. Anderson, PhD This publication provides readers with a thorough understanding of enzyme-inhibitor evaluation to assist them in their efforts to discover and optimize novel drug therapies. Key topics such as competitive, noncompetitive, and uncompetitive inhibition, slow binding, tight binding, and the use of Hill coeffi...
