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The Inflamed Mind
Depression will be the single biggest cause of disability worldwide, in the next 20 years. But treatment for it has not changed much in the last three decades. In the realm of psychiatry, time has apparently stood still... until now.In this game-changing book, Professor Edward Bullmore reveals the breakthrough new science on the link between mental depression and physical inflammation. He explains how and why mental disorders can have their roots in the immune system and explores a whole new way of looking at how mind, brain and body all work together in a sometimes misguided effort to help us survive in a hostile world.
Fundamentals of Brain Network Analysis
Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain...
The Diagnosis of Psychosis
Psychosis has many causes. Psychiatrists typically receive the most thorough training in its diagnosis, but the diagnosis of psychosis secondary to nonpsychiatric conditions is not often emphasized. An understanding of the underlying cause of psychosis is important for effective management. The Diagnosis of Psychosis bridges the gap between psychiatry and medicine, providing a comprehensive review of primary and secondary causes of psychosis. It covers both common and rare causes in a clinically focused guide. Useful both for teaching and reference, the text covers physical and mental state examination, describes key investigations, and summarizes the non-psychiatric features of medical conditions causing psychosis. Particularly relevant for psychiatrists and trainees in psychiatry, this volume will also assist neurologists and general physicians who encounter psychosis in their practice.
Textbook of Immunopsychiatry
The rapidly growing field of immunopsychiatry combines expertise and insights from immunology, psychiatry and neuroscience to understand the role of inflammation and other immune processes in causing and treating mental illness. This represents a major shift in mental health science, traditionally focused on psychological and neuronal mechanisms of depression, psychosis and dementia. This book provides the first comprehensive overview of recent, inter-disciplinary research linking disordered function of the immune system to the brain and mental illness. It offers a broad and deep perspective on the implications of immune system involvement in psychiatric disorders, including a balanced focus on basic science and clinical applications. Chapters cover the scientific evidence linking immune processes to major mental illnesses such as schizophrenia, depression, anxiety and dementia. An invaluable guide for graduate students, doctors in training, scientific researchers and others interested in the link between the immune system and mental health.
Statistical Parametric Mapping: The Analysis of Functional Brain Images
In an age where the amount of data collected from brain imaging is increasing constantly, it is of critical importance to analyse those data within an accepted framework to ensure proper integration and comparison of the information collected. This book describes the ideas and procedures that underlie the analysis of signals produced by the brain. The aim is to understand how the brain works, in terms of its functional architecture and dynamics. This book provides the background and methodology for the analysis of all types of brain imaging data, from functional magnetic resonance imaging to magnetoencephalography. Critically, Statistical Parametric Mapping provides a widely accepted concept...
Integrative Neuroscience and Personalized Medicine
This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavio...
Clinical Applications of Functional Brain MRI
Over the past few years FMRI has become one of the most widely used methods for imaging normal brain function, in turn becoming a valuable tool in the study of many psychiatric and neurological disorders. This book provides an overview of the latest FMRI research in a number of these disorders.
The Cambridge Companion to Oscar Wilde
The Cambridge Companion to Oscar Wilde offers an essential introduction to one of the theatre's most important and enigmatic writers. Although a general overview, the volume also offers some of the latest thinking on the dramatist and his impact on the twentieth century. Part One places Wilde's work within the cultural and historical context of his time and includes an opening essay by Wilde's grandson, Merlin Holland. Further chapters also examine Wilde and the Victorians and his image as a Dandy. Part Two looks at Wilde's essential work as playwright and general writer, including his poetry, critiques, and fiction, and provides detailed analysis of such key works as Salome and The Importance of Being Earnest among others. The third group of essays examines the themes and factors which shaped Wilde's work and includes Wilde and his view of the Victorian woman, Wilde's sexual identities, and interpreting Wilde on stage. This 1997 volume also contains a detailed chronology of Wilde's work, a guide to further reading, and illustrations from important productions.
Network Approaches to Diseases of the Brain
This book covers novel approaches using networks and oscillations and it will serve as a catalyst for translating these exciting advancements into the clinical arena. This collection of articles aims to accelerate the widespread clinical translation of network approaches by providing practical information accessible to clinicians in neurology and psychiatry - fields that are uniquely poised to implement these developments in clinical treatment of brain diseases. It should be a useful resource for researchers and working professionals in neurological and psychiatric academic centers.
Losing Our Minds
The exponential increases in neurodevelopmental disorders implicate both genetic causes and environmental factors. Flame-retardants, pesticides, plasticizers, and other every-day products contain chemicals shown to affect thyroid hormone signaling, which if disrupted can result in significant impairment to IQ. Across entire populations, such effects spell large-scale social and economic consequences. In this book Barbara Demeneix suggests what can and must be done to halt and reverse this disturbing trend.
