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Exploiting the inherent combinatorial mechanism in the biosynthesis of antibodies, an almost limitless variety of biocatalysts may be generated. Catalytic antibodies are capable of performing almost any type of reaction with high selectivity and stereospecificity. Here, the pioneers in the use of catalytic antibodies review the entire scope of this interdisciplinary field, covering such topics as: * theoretical aspects of structure, mechanism and kinetics * practical considerations, from immunization techniques to screening methods * in vitro evolution and other modern approaches * applications from organic synthesis to medical uses. Backed by the leading authorities in antibody catalysis, this is the first book to provide such comprehensive coverage and constitutes a prime reference for biochemists, organic chemists, biotechnologists and biomedical researchers.
The area of biologically inspired computing, or biological computation, involves the development of new, biologically based techniques for solving difficult computational problems. A unified overview of computer science ideas inspired by biology, Biological Computation presents the most fundamental and significant concepts in this area. In the book, students discover that bacteria communicate, that DNA can be used for performing computations, how evolution solves optimization problems, that the way ants organize their nests can be applied to solve clustering problems, and what the human immune system can teach us about protecting computer networks. The authors discuss more biological example...
Here, numerous winners of the Wolf prize from all chemical disciplines provide an overview of the new ideas and approaches that will shape this dynamic science over the forthcoming decades and so will have a decisive influence on our living conditions. This glimpse of the future is naturally based on the findings granted us by the rapid increase in chemical research during the 20th century. It may be said that a silent "revolution" took place, the positive results of which are still not fully predicted. For example, chemists in research laboratories nowadays are able to develop drugs in increasingly short times to treat diseases once thought incurable. They can design new materials that withstand extreme conditions, and predict the properties of compounds that no one has even seen yet. In this exceptional book those breakthroughs of modern chemistry are illustrated and explained by leading scientists. It stems from the high-quality papers given at the prestigious ceremony to accompany the presentation of the 20th Wolf Prize. It is an extraordinary source for every chemist in industry and academia to get an overview of the highlights of modern chemistry.
This book constitutes the thoroughly refereed postproceedings of the 10th International Workshop on DNA Based Computers, DNA10, held in Milano, Italy in June 2004. The 39 revised full papers presented were carefully selected during two rounds of reviewing and improvement from an initial total of 94 submissions. The papers address all current issues in DNA based computing and biomolecular computing ranging from theoretical and methodological issues to implementations and experimental aspects.
Organized to provide maximum utility to the bench synthetic chemist. The editor is well-known for his work in exploring, developing, and applying organopalladium chemistry. Contributors include over 24 world authorities in the field.
This e-book is an overview of recent advances in the realm of kidney transplantation. The volume discusses developments in surgical procedures while presenting a perspective on possibilities for kidney transplant research in the future. The e-book is a c
The arrival of the participatory web 2.0 has been hailed by many as a media revolution, bringing with it new tools and possibilities for direct political action. Through specialised online platforms, mainstream social media or blogs, citizens in many countries are increasingly seeking to have their voices heard online, whether it is to lobby, to support or to complain about their elected representatives. Politicians, too, are adopting "new media" in specific ways, though they are often criticised for failing to seize the full potential of online tools to enter into dialogue with their electorates. Bringing together perspectives from around the world, this volume examines emerging forms of citizen participation in the face of the evolving logics of political communication, and provides a unique and original focus on the gap which exists between political uses of digital media by the politicians and by the people they represent.
This book highlights the intrinsic structures of all kinds of energetic compounds and some structure–property relationships therein. Energetic materials are a class of energy materials that can transiently release a large amount of gases and heat by self-redox after stimulated and usually refer to explosives, propellants and pyrotechnics. Nowadays, in combination with various theories and simulation-aided material design technologies, many new kinds of energetic materials like energetic extended solids, energetic ionic salts, energetic metal organic frames, energetic co-crystals and energetic perovskites have been created, in addition to traditional energetic molecular crystals. It is some...
A world-leading military strategist and an IDF insider explain the improbable success of the Israeli armed forces. When the Israel Defense Forces was established in May 1948, it was small, poorly equipped, and already at war. Lacking sufficient weaponry or the domestic industrial base to produce it, the newborn military was forced to make do with whatever it could get its hands on. That spirit of improvisation carried the IDF to a decisive victory in the First Arab-Israeli War. Today the same spirit has made the IDF the most powerful military in the Middle East and among the most capable in the world. In The Art of Military Innovation, Edward N. Luttwak and Eitan Shamir trace the roots of th...