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Membrane Trafficking
As membrane trafficking research has expanded over the past thirty years, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells. This book reflects these advances by devoting one section of the book to yeast cells and the other to mammalian cells, with each section providing both classic and cutting-edge techniques to study macromolecular transport across the membranes.
Biochemistry of Signal Transduction in Myocardium
The chapters in this volume are the Proceedings of the Satellite Symposium of the XVIth World Congress of the International Society for Heart Research on `Signal Transduction in Normal and Diseased Myocardium' which was held in Rotterdam at the Faculty of Medicine & Health Sciences of the Erasmus University, June 30 and July 1, 1995. Diverse and distinct auto-, para-, and endocrine stimuli arriving at the surface of endothelium, smooth muscle cells, cardiomyocytes and fibroblasts within the myocardium, engage cell type-specific receptors, which lead to transmission of signals across the cell plasma membrane and result in the production and activation of second messengers. The most common mec...
SARS- and Other Coronaviruses
In 2003, the word "coronavirus" spread across the globe, somewhat further than the virus that sparked the panic. In this book, expert researchers examine these devastating viruses through 23 state-of-the-art, widely applicable protocols with minute detail. Comprehensive and cutting-edge, the book serves as an ideal guide for all virologists and especially for those working with coronaviruses. Written by international experts, this book is relevant to a wide array of professions.
Pharmacology of the WNT Signaling System
This book reflects the state of the art of our understanding of the WNT signaling system, which comprises a network of signaling pathways initiated by the secreted WNT lipoglycoproteins, which are crucial for embryonal development, stem cell regulation, tissue homeostasis and repair. Dysfunction of this evolutionarily conserved signaling system leads to many diseases including developmental disorders, diverse forms of cancer, fibrosis, neurodegenerative disease and many more. The WNT signaling system is built upon 19 mammalian, secreted WNT lipoglycoproteins that interact with a plethora of distinct receptors, such as the G protein-coupled receptors called Frizzleds (FZD1-10), LDL receptor-l...
Organoids
This detailed volume addresses the challenge of how to instruct stem/early progenitor cells to progress through appropriate steps to generate functional 3-dimensional organs, one of the outstanding issues in regenerative medicine. The field of organoids is geared towards defining and demonstrating the in vitro conditions that achieve this goal. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Organoids: Stem Cells, Structure, and Function serves as an aid to researchers working in this vital area of research.
A French Huguenot Legacy
From the Knights Templar to serving in the militia under George Washington, the Huguenot's have been keepers of the faith, fighters for freedom, and left their mark on history. The Huguenots were massacred in France in the 17th century when the Royals declared one king, one law, one religion. Fleeing for their lives, and for the right to worship as Protestants, many walked away from lives of nobility. Jacques Guyon settled on Staten Island; Louis Guion settled first in Rye, then New Rochelle, NY. Follow their journeys and the lives of their descendants in a true French-American saga. Of particular interest to genealogists, with a supporting appendix, especially for those families who intermarried with the Guion's.
Edmonson Co, KY
(From the Foreword) The purpose of this book is to recognnize and honor an individual's history as well as the history of Edmonson County families. It is felt that this goal was met in the Family History of Edmonson County.
Plant Hormones
Given the rapid increase in our understanding of plant hormone biology, this second edition of a comprehensive review could not have come at a better time. In its chapters, expert researchers explore the latest approaches to understanding plant hormone action.
The English Reports: King's Bench Division
V. 1-11. House of Lords (1677-1865) -- v. 12-20. Privy Council (including Indian Appeals) (1809-1865) -- v. 21-47. Chancery (including Collateral reports) (1557-1865) -- v. 48-55. Rolls Court (1829-1865) -- v. 56-71. Vice-Chancellors' Courts (1815-1865) -- v. 72-122. King's Bench (1378-1865) -- v. 123-144. Common Pleas (1486-1865) -- v. 145-160. Exchequer (1220-1865) -- v. 161-167. Ecclesiastical (1752-1857), Admiralty (1776-1840), and Probate and Divorce (1858-1865) -- v. 168-169. Crown Cases (1743-1865) -- v. 170-176. Nisi Prius (1688-1867).
