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This book provides the first comprehensive review of viral genome replication strategies, emphasizing not only pathways and regulation but also the structure-function, mechanism, and inhibition of proteins and enzymes required for this process.
This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.
This book consists of tributes written by friends, colleagues, teachers, students and family members of Professor Shu Chien on the occasion of his 70th birthday, which was celebrated in San Diego, California on 23 June 2001, and in Taipei, Taiwan on 12 August 2001. Following those events, a collection of articles was submitted. Together with the precious, memorable photographs, these articles provide a valuable summary of the life and deeds of this internationally acclaimed scientist who has made major impacts in the United States, mainland China and Taiwan -- indeed, the whole world. In response to these excellent, moving articles, Professor Shu Chien has written a piece that encompasses his entire life, from early childhood to the present. This book constitutes a most valuable biography, full of sentiment and inspiration. Researchers, academics, postdoctoral fellows, graduate students and undergraduates in bioengineering, physiology, biophysics, molecular and cellular biology, and related fields.
The report says that important organizational changes are needed at the National Institutes of Health to ensure the agency meets future challenges effectively. In particular, the report advises NIH to devote additional resources to innovative interdisciplinary research that reflects its strategic objectives and cuts across all agency's institutes and centers. The report recommends that Congress should establish a formal process for determining how specific proposals for changes in the number of NIH agencies and centers should be addressed.
This publication represents the culmination of the National Academies Keck Futures Initiative (NAKFI), a program of the National Academy of Sciences, the National Academy of Engineering, and the National Academy of Medicine supported by a 15-year, $40 million grant from the W. M. Keck Foundation to advance the future of science through interdisciplinary research. From 2003 to 2017, more than 2,000 researchers and other professionals across disciplines and sectors attended an annual "think-tank" style conference to contemplate real-world challenges. Seed grants awarded to conference participants enabled further pursuit of bold, new research and ideas generated at the conference.
The advice in this book is useful for many types of grant applications, business plans, journal articles, and research reports.