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Stem Cells and the Future of Regenerative Medicine
Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. ...
The Ethics of Embryonic Stem Cell Research
Embryonic stem cell research holds unique promise for developing therapies for currently incurable diseases and conditions, and for important biomedical research. However, the process through which embryonic stem cells are obtained involves the destruction of early human embryos. Katrien Devolder focuses on the tension between the popular view that an embryo should never be deliberately harmed or destroyed, and the view that embryonic stem cell research, because of its enormous promise, must go forward. She provides an in-depth ethical analysis of the major philosophical and political attempts to resolve this tension. One such attempt involves the development of a middle ground position, whi...
The Embryo Research Debate
Scientific research involving human embryos was a major topic of public debate in Britain during the 1980s. Despite strong support from the scientific community, embryo research was initially condemned by many ordinary people as well as by special interest groups, and came close to being banned by Act of Parliament. Michael Mulkay describes the dynamics of the parliamentary struggle over the future of embryo research, focusing on such issues as: the clash between the anti-abortion and pro-research lobbies; the tactics of the Government; political ideology; the media's role; the importance of gender; religion; the impact of science fiction; the lure of medical advance; and the difficulty of maintaining ethical control. He explains how the advocates of embryo research eventually triumphed, and ends with an examination of the cultural tensions which linger after the debate.
Embryo Research in Pluralistic Europe
Recent advances in techniques and understanding in the fields of genetics, embryology and reproductive biology have opened up new ways to treat a wide range of medical problems. They range from new options for infertility treatment and pre-implantation genetic diagnosis to stem-cell-based therapies for debilitating diseases. Since all these approaches involve the manipulation of human gametes, embryos or embryonic cells, and could also permit more contentious uses, they have stimulated a controversial debate as to what aims are desirable and to what extent experiments on human embryos are morally permissible, if permissible at all. The situation is further complicated by the fact that scient...
The Human Embryo Research Debates
Research on the early human embryo has long been recognized as essential to progress in a host of biomedical areas from reproductive medicine to the treatment of pediatric cancers. Now, with the possibility of stem cell research and cell replacement therapies, embryo research holds out the promise of cures for many serious disease conditions such as diabetes and Alzheimer's disease. Despite its importance, however, human embryo research has met powerful opposition. Drawing on his experience as a member of the NIH's Human Embryo Research Panel, Green offers a first-hand account of the embryo research debates. In telling this story, he periodically pauses to reflect on some of the leading phil...
Cloning and the Future of Human Embryo Research
Hailed as revolutionary, the prospect of human cloning is actually the next logical step in a series of developments in reproductive technology that began with the first test-tube baby in 1978. This book addresses the debates over cloning in the context of new reproductive technology and human embryo research. It examines the status of preimplantation embryos, the ethical issues related to cloning and embryo research, and the formulation of public policy.
Stem Cell Research
This volume brings together essays by an internationally distinguished and diverse group of scholars. Contributors thoughtfully explore the ethical, public policy, and scientific implications of embryonic and adult stem cell research. Part one of the book offers a variety of scientific and public policy perspectives, including essays on stem cell plasticity and using umbilical cord blood as an alternative source of pluripotent stem cells. Part two vigorously examines the ethics of stem cell research and considers issues of social justice, morality, and public policy. Scientific alternatives, a natural law perspective regarding federal funding, and a discussion of the possible moral complicity of Catholic researchers are among the distinctive contributions made to the stem cell research debate by this collection. The objective and balanced discussions contained in this volume serve as an accessible introduction to the bioethical questions, issues, and problems surrounding stem cell research.
Examining the State of the Science of Mammalian Embryo Model Systems
Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.
Guidelines for Human Embryonic Stem Cell Research
Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.
Scientific and Medical Aspects of Human Reproductive Cloning
Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.
