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Energetics of Biological Macromolecules, Part D
This volume focuses on the cooperative binding aspects of energetics in biological macromolecules. Methodologies such as NMR, small-angle scattering techniques for analysis, calorimetric analysis, fluorescence quenching, and time resolved FRET measurements are discussed. *Methods for Evaluating Cooperativity in a Dimeric Hemoglobin*Multiple-Binding of Ligands to a Linear Biopolymer*Fluorescence Quenching Methods to Study Protein-Nucleic Acid Interactions*Linked Equilibria in Biotin Repressor Function: Thermodynamic, Structural and Kinetic Analysis
Structure and Function of Invertebrate Oxygen Carriers
Oxygen binding proteins are large multi unit proteins ideally suited for the study of structure function relationships in biological molecules. This book, based on a Symposium at the Xth International Biophysics Congress in 1990, provides a synthesis of recent advances in our knowledge of invertebrate oxygen carriers such as hemoglobins, hemocyanins, and hemorythrins. Comprehensive reviews are combined with new research results of importance to all biochemists and molecular biologists interested in oxygen carriers in general, their gene structure and comparative biochemistry. Of particular value are the studies of invertebrate oxygen binding proteins which perform their function and have structures vastly different from the vertebrate hemoglobins and myoglobins, as well as numerous examples of modern molecular techniques as applied to research on this diverse group of proteins.
Dioxygen Binding and Sensing Proteins
Following their own brilliant careers in haeme protein research, the outstanding scientists Jonathan and Beatrice Wittenberg continue to provide inspiration to the research community in the study of oxygen-binding proteins. Their research has provided the intellectual stimulus to bring together scientists from all over the world with the common goal of developing fascinating new ideas and performing innovative experiments. This book is dedicated to Jonathan’s and Bea’s lifetime careers. It further illuminates the facts and ideas which dot the paths they traced in Biochemistry and Physiology, elaborating on how these landmark achievements were made and how the haeme proteins community still refers to them. With the field of haeme protein science such a flourishing area, the contributors to this book predict Jonathan and Bea, having played such a seminal role, will continue to be key figures for quite some time to come.
Pietro Blaserna and the Birth of the Institute of Physics in Rome
This book draws upon a wealth of archival material to present the life and achievements of Pietro Blaserna, a “gentleman scientist” whose greatest legacy is considered to be the Institute of Physics on the Via Panisperna in Rome, of which he was the creator and first director. Both in this role and as President of the Accademia dei Lincei, Blaserna contributed enormously in establishing a sound institutional base for the further development of physics in Italy. Starting from an accurate historical reconstruction of the scientific, social, and political context, the author presents the different phases of Pietro Blaserna’s life and career. As a multifaceted intellectual and a scientist ...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Drug-Nucleic Acid Interactions
This volume consolidates the key methods for studying ligand-nucleic acid interactions into a convenient source. Techniques that are examined range from biophysical and chemical approaches to methods rooted in molecular and cell biology.
Hydrogen Peroxide and Cell Signaling, Part C
This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the third of three volumes on hydrogen peroxide and cell signaling, and includes chapters on such topics as the biological chemistry of hydrogen peroxide, reactive oxygen species in the activation of MAP kinases, and investigating the role of reactive oxygen species in regulating autophagy. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers hydrogen peroxide and cell signaling Contains chapters on such topics as the biological chemistry of hydrogen peroxide, reactive oxygen species in the activation of MAP kinases, and investigating the role of reactive oxygen species in regulating autophagy
Regulation of Phosphate and Mineral Metabolism
We are pleased to present to our readers the Proceedings of the Fifth International Workshop on Phosphate and Other Minerals which was held in New York City, New York, U.S.A during September 23-27,1981. It was hosted by Joseph M. Letteri, M.D., Professor of Medicine at the State University of New York at Stonybrook School of Medicine, and Chief, Division of Nephrology, Nassau County Medical Center. As in the previous Workshops, this meeting provided an oppor tunity for interested scientists from interrelated fields, including nephrology, endocrinology, physiology, biochemistry and nutrition, to get together and discuss the recent advances in the field of phosphate and mineral metabolism. The...
