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Currently, the assessment of functional immunological relevance is mainly done in animal models. Motivation to work on non-animal methods, or new approach methods (NAM), stems from economical and ethical considerations, and is supported by public pressure. Importantly, the translational gap between results obtained in animal studies and clinical trials in humans (the ‘valley of death’), combined with the reproducibility crisis in science, also provide strong scientific arguments to work on novel, robust, human-based methodology. The field of immunology confronts NAM scientists with specific challenges. Firstly, immunological responses require several cell types in different locations for...
One of Springer’s Major Reference Works, this book gives the reader a truly global perspective. It is the first major reference work in its field. Paleoclimate topics covered in the encyclopedia give the reader the capability to place the observations of recent global warming in the context of longer-term natural climate fluctuations. Significant elements of the encyclopedia include recent developments in paleoclimate modeling, paleo-ocean circulation, as well as the influence of geological processes and biological feedbacks on global climate change. The encyclopedia gives the reader an entry point into the literature on these and many other groundbreaking topics.
Teaching Creative Writing in Canada maps the landscape of Creative Writing programmes across Canada. Canada’s position, both culturally and physically, as a midpoint between the two major Anglophone influences on Creative Writing pedagogyy—the UK and the USA—makes it a unique and relevant vantage for the study of contemporary Creative Writing pedagogy. Showcasing writer-professors from Canada’s major Creative Writing programmes, the collection considers the climate-crisis, contemporary workshop scepticism, curriculum design, programme management, prize culture, grants and interdisciplinarity. Each chapter concludes with field-tested writing advice from many of Canada’s most influential professors of fiction, poetry, creative nonfiction and drama. This authoritative volume offers an important national perspective on contemporary and timeless issues in Creative Writing pedagogy and their varied treatment in Canada. It will be of valuable to other creative teachers and practitioners, those with an interest in teaching and learning a creative art and anyone working on cultural and educational landscapes.
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Braun (geography, U. of Minnesota) provides a new viewpoint on the complex cultural, political, and intellectual forces involved in the forest policies of British Columbia. Employing poststructuralist theory and using the 1993 protests over logging in Clayoquot Sound as his starting point, Braun assesses the colonial thinking behind 19th- century forest policies, the struggles of native peoples to regain their spaces, the assertion of so-called rational forest management as a new version of colonialism, the Western Canada Wilderness Committee's use of nature photography to promote their notion of pristine wilderness, ecotourism, and the continued impact of the vision of early 20th-century painter Emily Carr. Annotation copyrighted by Book News Inc., Portland, OR.
This richly illustrated book is both a visitor’s guide to one of southwestern Ontario’s most striking landforms – the Elora Gorge on the Upper Grand River – and a thorough, accessible introduction to its natural and recent human history. The book introduces rivers that flow in bedrock, between rock walls and through precipitous gorges, unlike the subdued terrain that the last Ice Age bequeathed most of southwestern Ontario. It then leads the visitor to three viewpoints on and three excursions through the gorge, with a wealth of information about its rocks, fossils, caves, cliffs, rockslides, rockfalls, floods and erosional processes. It takes the reader through five “ages” of the...
In recent years, interest in Neoproterozoic glaciations has grown as their pivotal role in Earth system evolution has become increasingly clear. One of the main goals of the IGCP Project number 512 was to produce a synthesis of newly available information on Neoproterozoic successions worldwide. This Memoir consists of a series of overview chapters followed by site-specific chapters. The overviews cover key topics including the history of research on Neoproterozoic glaciations, identification of glacial deposits, chemostratigraphic techniques and datasets, palaeomagnetism, biostratigraphy, geochronology and climate modelling. The site specific chapters include reviews of the history of research on these rocks and up-to-date syntheses of the structural framework, tectonic setting, palaeomagnetic & geochronological constraints, physical, biological, and chemical stratigraphy, and descriptions of the glaciogenic and associated strata, including economic deposits.
The Encyclopedia of Soil Science provides a comprehensive, alphabetical treatment of basic soil science in a single volume. It constitutes a wide ranging and authorative collection of some 160 academic articles covering the salient aspects of soil physics, chemistry, biology, fertility, technology, genesis, morphology, classification and geomorphology. With increased usage of soil for world food production, building materials, and waste repositories, demand has grown for a better global understanding of soil and its processes. longer articles by leading authorities from around the world are supplemented by some 430 definitions of common terms in soil sciences.