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SAR
This book focuses on the quantitative structure-activity relationship of the disposition and activities of various pharmacological groups. It presents a systematic approach for linking different side effect of drugs to their molecular structure and physiochemical properties.
Traditional Chinese Medicine
Traditional Chinese medicine has a strong scientific basis, but the science of these important preparations is often rarely discussed. Western approaches often simplify traditional Chinese medicine to drug discovery in Chinese plants, however, the majority of traditional Chinese medications use complex mixtures of plant extracts, rather than single purified drugs. The combination of different extracts is based on yin, yang and chi theories, which are often poorly understood in the West. Yin and yang are known to be the balance of agonists and antagonists, whereas chi derives from signalling processes in the body and regulates bodily functions. Traditional Chinese medical practitioners unders...
Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques
Volume 46 of this well-established and acclaimed book series contains seven comprehensive reviews by internationally recognized experts. They will provide the reader with up-to-date information. Contents: N.K. Hollenberg and S.W. Graves: Endogenous sodium pump inhibition: Current Status • R.B. McCall: Neurotransmitters involved in the central regulation of the cardivascular system • W.T. Jackson and J.H. Fleisch: Development of novel anti- inflammatory agents: A pharmacologic perspective on leukotrienes and their receptors • M. Margaglione, E. Grandone, F.P. Mancini and G. Di Minno: Drugs affecting plasma fibrinogen levels. Implications for new antithrombotic strategies • N. Seiler, A. Hardy and J.P. Moulinoux: Aminoglycosides and polyamines: Targets and effects in the mammalian organism of two important groups of natural aliphatic polycations • J. Claghorn and M.D. Lesem: Recent developments in antidepressant agents • E.J. Lien, A. Das and L.L. Lien: Immunopharmacological and biochemical bases of Chinese herbal medicine • Index Vol. 46 • Index of titles Vols. 1-46 • Author and paper index Vols. 1-46.
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques
Volume 43 of «Progress in Drug Research» contains five reviews and the various indexes which facilitate its use and establish the connection with the previous volumes. The articles in this volume deal with high cholesterol blood levels and other dyslipidemias; search of ideal antihypertensive drugs; the natural PQlyamines and the immune system; biologically active quinazolones and with production and action of interferons. In the 35 years the PDR has existed, the Editor has enjoyed the valuable help and advice of many colleagues. Readers, the authors of the reviews, and last but not least, the reviewers have all contributed greatly to the success of this series. Although the comments recei...
Progress in Drug Research
In the first years of the existence of this series of monographs, during the so-called "Golden Age" of drug research, the majority of the pa pers published were mainly concerned with the traditional domains of drug research, namely chemistry, pharmacology, toxicology and pre clinical investigations. The series' aim was to give coverage to impor tant areas of research, to introduce new active substances with thera peutic potential and to call attention to unsolved problems. This objective has not changed. The table of contents of the present volume makes evident, however, that the search for new medicines has become increasingly complex, and additional, new disciplines have entered the resear...
Progress in Drug Research
Jay A. Glasel: Drugs, the human genome, and individual-based medicine.- Vera M. Kolb: Herbal medicine of Wisconsin Indians.- Paul L. Skatrud: The impact of multiple drug resistance (MDR) proteins on chemotherapy and drug discovery.- John W. Ford, Edward B. Stevens, J. Mark Treherne, Jeremy Packer and Mark Bushfield: Potassium channels: Gene family, therapeutic relevance, high-throughput screening technologies and drug discovery.- David T. Wong and Frank P. Bymaster: Dual serotonin and noradrenaline uptake inhibitor class of antidepressants - Potential for greater efficacy of just hype?.- Satya P. Gupta: Advances in QSAR studies of HIV-1 reverse transcriptase inhibitors.
