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Symmetric designs are an important class of combinatorial structures which arose first in the statistics and are now especially important in the study of finite geometries. This book presents some of the algebraic techniques that have been brought to bear on the question of existence, construction and symmetry of symmetric designs - including methods inspired by the algebraic theory of coding and by the representation theory of finite groups - and includes many results. Rich in examples and containing over 100 problems, the text also provides an introduction to many of the modern algebraic approaches used, through six lengthy appendices and supplementary problems. The book will be of interest to both combinatorialists and algebraists, and could be used as a course text for a graduate course.
Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980's, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA data...
Nearly four decades ago Richard Dawkins published The Selfish Gene, famously reducing humans to “survival machines” whose sole purpose was to preserve “the selfish molecules known as genes.” How these selfish genes work together to construct the organism, however, remained a mystery. Standing atop a wealth of new research, The Society of Genes now provides a vision of how genes cooperate and compete in the struggle for life. Pioneers in the nascent field of systems biology, Itai Yanai and Martin Lercher present a compelling new framework to understand how the human genome evolved and why understanding the interactions among our genes shifts the basic paradigm of modern biology. Contr...
When DNA profiling was first introduced into the American legal system in 1987, it was heralded as a technology that would revolutionize law enforcement. As an investigative tool, it has lived up to much of this hype—it is regularly used to track down unknown criminals, put murderers and rapists behind bars, and exonerate the innocent. Yet, this promise took ten turbulent years to be fulfilled. In Genetic Witness, Jay D. Aronson uncovers the dramatic early history of DNA profiling that has been obscured by the technique’s recent success. He demonstrates that robust quality control and quality assurance measures were initially nonexistent, interpretation of test results was based more on assumption than empirical evidence, and the technique was susceptible to error at every stage. Most of these issues came to light only through defense challenges to what prosecutors claimed to be an infallible technology. Although this process was fraught with controversy, inefficiency, and personal antagonism, the quality of DNA evidence improved dramatically as a result. Aronson argues, however, that the dream of a perfect identification technology remains unrealized.
Australian scholars of genetics, law, and agricultural biotechnology, present a handbook of DNA-based evidence for the legal, forensic, and law-enforcement professions. Explains to non-scientists how the genetic material in tissue residues is analyzed to provide direct identification of an individual. Describes the principles and procedures, the scientific aspects and legal implications of obtaining tissue samples, and problems that can arise in interpretation. Annotation copyrighted by Book News, Inc., Portland, OR
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, ...
Provided by Horace Freeland Judson, author of the bestselling Eighth Day of Creation. The book's broad and balanced coverage and the expertise of its contributors make The Code of Codes the most comprehensive and compelling exploration available on this history-making project.
In The Poetics of DNA, Judith Roof examines the rise of this powerful symbol and the implications of its ascendancy for the ways we thinkÑabout ourselves, about one another, and about the universe. A hyperbolized notion of DNA has become a vector, Roof argues, through which older ways of thinking can merge with the new, advancing long-discredited and insidious ideas.
Exploring Nanosyntax is the first in-depth introduction to the framework of nanosyntax. Deploying the cartographic "one feature - one head" maxim, the framework decomposes morphosyntactic structure, laying bare the building blocks of the universal functional sequence. This volume presents the framework's constitutive tools and principles, and explains how nanosyntax relates to cartography and to Distributed Morphology. It also illustrates how nanosyntactic tools and principles can e applied to a range of empirical domains of natural language. Comprising twelve original contributions by leaders of the field, the volume provides a range of cross-linguistic investigations that contribute to a better understanding of the functional sequence. Book jacket.
For more than 40 years, Computerworld has been the leading source of technology news and information for IT influencers worldwide. Computerworld's award-winning Web site (Computerworld.com), twice-monthly publication, focused conference series and custom research form the hub of the world's largest global IT media network.