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Molecular Oncology
Reviews the origins of molecular oncology, including technologies for cancer analysis, key pathways in human malignancies, and available pharmacologic therapies.
Tumor Microenvironment
The way a cell undergoes malignant transformation should meet their capacity of surviving in the microenvironment of the organ where the cancer will develop. Metabolic adaptation is for sure one of the criteria that must be accomplished, driven by metabolic plasticity that allows the adaptation of cancer cells to the availability of energy and biomass sources that will sustain cell survival and proliferation. Each human organ has a particular microenvironment which depends on several cell types and in some cases also on symbiotic microorganisms. These biological partners are constantly sharing organic compounds and signaling molecules that will control mitogenesis, cell death and differentia...
Forkhead Transcription Factors
Forkhead Transcription Factors: Vital Elements in Biology and Medicine provides a unique platform for the presentation of novel work and new insights into the vital role that forkhead transcription factors play in multiple systems throughout the body. Leading international authorities provide their knowledge and insights to offer a novel perspective for translational medicine that highlights the role of forkhead genes and proteins that may have the greatest impact for the development of new strategies for a broad array of disorders. Equally important, Forkhead Transcription Factors: Vital Elements in Biology and Medicine clearly sets a precedent for the necessity to understand the diverse and complex nature of forkhead proteins since this family of transcription factors can limit as well as foster disease progression depending upon the cellular environment. The presentation and discussion of innovative studies and especially those that examine previously unexplored pathways that may influence clinical survival and longevity offer an exciting approach to address the potential of forkhead transcription factors for new therapeutic avenues in multiple disciplines.
Cancer Research
None
The Journal of Cell Biology
No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-
Your Healthy Pregnancy with Thyroid Disease
At minimum, 27 million Americans have thyroid disease. Despite being the majority of thyroid sufferers, women rarely know that thyroid problems increase their risk of pregnancy complications, including infertility, preeclampsia, miscarriage, premature delivery, and low birth weight. This awareness gap affects patients and doctors, who know little about the ramifications of an undiagnosed or under-treated thyroid condition on a mother and her unborn baby. Founder of HypothyroidMom.com Dana Trentini and thyroid health advocate and bestselling author Mary Shomon have both endured challenges with pregnancies due to thyroid disorders. In Your Healthy Pregnancy with Thyroid Disease, they team up to give readers the answers they need. With personal stories and cutting-edge medical advice from leading health practitioners, the book explains how to recognize thyroid symptoms, get properly diagnosed/treated, manage thyroid problems during pregnancy, overcome thyroid-related infertility, and deal with postpartum challenges.
