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Cholesterol
Experts investigate the biochemical and biomedical aspects of cholesterol, addressing its metabolism in normal and disease states. They discuss a broad range of topics, including key steps in the cholesterol biosynthetic pathway, and the role of cholesterol in cancer, atherosclerosis, and diseases of the nervous system. The book's comprehensive coverage also includes the pathological consequences and potential therapies for various disease states, and the development of new anti-atherogenic drugs.
Cardiovascular Specific Gene Expression
Improving our insights into the genetic predisposition to cardiovascular disease is one of the most important challenges in our field in the next millennium, not only to unravel the cause of disease but also to improve the selection of patients for particular treatments. Nowadays, for example, subjects with a cholesterol above a particular plasma level are exposed to a cholesterol lowering regime based upon the beneficial outcome of epidemiological studies which include subjects not prone to the disease, despite a plasma cholesterol above the accepted level. Identification of the patients who are genetically predisposed to the consequences of this disorder will reduce the number of subjects ...
Vascular Biology, Haemostasis and Extracellular Nucleic Acids in Vascular Diseases and Immunity. A Tribute to Klaus T. Preissner
Topic Editor Prof. Ritva Tikkanen Receives Research Funding From Neurogene Inc. and GC Pharma for Studies Unrelated to the Subject. Topic Editor Prof. Carl Blobel is Co-Inventor on a Patent Describing a Method of Identifying Agents for Combination With Inhibitors of iRhoms. He and the Hospital for Special Surgery (New York, USA) are Investigating Suitable Approaches to Identify iRhom Inhibitors, and are Co-Founders of a Small Company Called SciRhom in Munich to Pursue These Efforts. Topic Editor Dr. Sylvia Fischer Declares no Competing Interests With Regards to the Research Topic Subject.
Nonviral Vectors for Gene Therapy
The purpose of this volume of Methods in Molecular Medicine is to set forth examples of the great variety of techniques and applications that are now emerging in the field of nonviral gene therapy. The book emphasizes not only specific approaches to gene delivery but, in particular, the best current me- ods to prepare, handle, and characterize gene delivery agents. These topics are of very broad importance since gene therapy evolves from its mostly ac- emy-based experimental and clinical research to the ever increasing number of industry-driven programs directed toward commercial development. S- cessful introduction of nonviral gene therapy agents into the clinic should be expected to requir...
Women in Cytokines and Soluble Mediators in Immunity
We are delighted to present the inaugural Frontiers in Immunology “Women in Cytokines and Soluble Mediators in Immunity” series of article collections. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and Science, Technology, Engineering and Mathematics (STEM) research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.
Hepatology
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