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Lysosomal Storage Disorders
The knowledge of lysosomal biology and the consequences of its dysfunction have increased dramatically in the past 60 years. This book describes the nature of the lysosomal dysfunction and diseases as well as potential future treatments and therapies. Disease specific chapters provide thorough reviews of the clinical features of lysosomal storage disorders, their molecular basis and the commercial or experimental therapeutic approaches sought in this area. This is an invaluable resource for researchers in biochemical and molecular genetics, enzyme therapy, and gene transfer.
Fugitive Shoes
Driving across the Arizona desert, Sally Jasper collides with a man who sprints suddenly out of the sand. The man - an illegal Mexican immigrant - is killed upon impact. Haunted by a rising ghost of guilt, Sally vows to set things right again. She soon learns that the dead man was being chased, and the gang of vigilantes who were pursuing him is as dangerous as they are unpredictable. Sally realizes she has something in common with the dead stranger: a yearning for freedom. This desire leads her to form an unlikely rock-n'-roll band called Radio. Sally uses the band's performances as a front to conceal her perilous plan to smuggle a Mexican family across the border. But her task is complicated by her budding romance with an Immigration officer. Her days become a minefield, where one misstep will cost her everything she holds dear. Fugitive Shoes is a story of three women's efforts to let go of the past, to find unexpected love, to mingle with dangerous people, and to thwart the law when the law seems wrong. Most of all, it is a story of libertad. Freedom.Erin O'Rourke lives in the American southwest, and is the author of the best-selling novel, Seeing Pink.
The Handbook of Hispanic Linguistics
Reflecting the growth and increasing global importance of the Spanish language, The Handbook of Hispanic Linguistics brings together a team of renowned Spanish linguistics scholars to explore both applied and theoretical work in this field. Features 41 newly-written essays contributed by leading language scholars that shed new light on the growth and significance of the Spanish language Combines current applied and theoretical research results in the field of Spanish linguistics Explores all facets relating to the origins, evolution, and geographical variations of the Spanish language Examines topics including second language learning, Spanish in the classroom, immigration, heritage languages, and bilingualism
Joe Blackburn's a Clown's Log
Joseph Blackburn, a clown who juggled on horseback, took a professional trip to England in 1838, accompanied by the noted American vaulter and bareback rider, Levi J. North. His account of their experiences abroad encompasses activity with the circuses of
Mexican American English
A comprehensive linguistic analysis of Mexican American English, introducing a model of the language shift that results within immigrant groups.
Methods in prosody
This book presents a collection of pioneering papers reflecting current methods in prosody research with a focus on Romance languages. The rapid expansion of the field of prosody research in the last decades has given rise to a proliferation of methods that has left little room for the critical assessment of these methods. The aim of this volume is to bridge this gap by embracing original contributions, in which experts in the field assess, reflect, and discuss different methods of data gathering and analysis. The book might thus be of interest to scholars and established researchers as well as to students and young academics who wish to explore the topic of prosody, an expanding and promising area of study.
Seeing Pink
Five women, angered by continuous acts of abuse and domestic oppression, garb themselves in pink robes and hoods and embark on a campaign of revenge; as their behavior becomes increasingly audacious, they accidentally kill a man, the son of a U.S. senator.
Spanish Diversity in the Amazon
Spanish Diversity in the Amazon focusses on Spanish varieties spoken in the Peruvian, Ecuadorean and Colombian Amazon, and this volume is the first of its kind. It introduces studies on theoretical, methodological and descriptive studies on linguistic, typological, ethnographic, and contact linguistics perspectives.
The Routledge Handbook of Sociophonetics
The Routledge Handbook of Sociophonetics is the definitive guide to sociophonetics. Offering a practical and accessible survey of an unparalleled range of theoretical and methodological perspectives, this is the first handbook devoted to sociophonetic research and applications of sociophonetics within and beyond linguistics. It defines what sociophonetics is as a field and offers views of what sociophonetics might become. Split into three sections, this book: • examines the suprasegmental, segmental, and subsegmental units that sociophoneticians study; • reveals the ways that sociophoneticians create knowledge and solve problems across a range of theoretical and practical applications; â...
