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Lysosomal Storage Disorders
The knowledge of lysosomal biology and the consequences of its dysfunction have increased dramatically in the past 60 years. This book describes the nature of the lysosomal dysfunction and diseases as well as potential future treatments and therapies. Disease specific chapters provide thorough reviews of the clinical features of lysosomal storage disorders, their molecular basis and the commercial or experimental therapeutic approaches sought in this area. This is an invaluable resource for researchers in biochemical and molecular genetics, enzyme therapy, and gene transfer.
Irish Studs
Twenty years after the murder of her father-an agent for British intelligence-and her mother's conviction of the crime, Fiona Cartwright, now a grown woman, returns to Ireland to prove her mother's innocence. In a case long closed and cold as Siberia, Fiona struggles to find clues to the real assassin. She helps thwart the family barrister, Sir Dylan Kerrigan, who is immersed in a treacherous plot to fund the IRA's plan to bomb the London Tower Bridge. Possessed by her need to solve the case, she confronts the secret society of the Shamrock Brotherhood, an organization long part of her father's life as a double agent. The answers are almost in place, but Fiona, faced anew with the tragedy of her mother's death, falls over the edge into drunkenness and despair. Her childhood nanny, Erin-whose lapse of memory prevented her from revealing her secrets is treated with a drug that loosens her tongue. Not until an unexpected accident knocks her unconscious is Fiona transported back to the night of the murder and she discovers the identity of the assassin.
Erin's Sons
From the time of the earliest European colonies, there were Irish settlers in the four provinces of Atlantic Canada--Newfoundland and Labrador, Prince Edward Island, New Brunswick, and Nova Scotia. Despite the flow of Irish through Atlantic Canada, the early records of these immigrants are fewer and less informative than those of New England and New York from the same period. "Erin's Sons: Irish Arrivals in Atlantic Canada 1761-1853" goes a long way toward rectifying this problem. Author Terrence M. Punch has combed through a wide-ranging and disparate group of sources-including newspaper articles and advertisements, local government documents and census records, church records, burial records, land records, military records, passenger lists, and more-to identify as many of these pioneers as possible and disclose where they came from in the Old Country. These sources often contain details that cannot be found in Irish records, where few census returns survived from before 1901, and where Catholic records began a generation or more after their counterparts in Atlantic Canada.
The Handbook of Clinical Linguistics
The new edition of the leading reference work on Clinical Linguistics, fully updated with new research and developments in the field The Handbook of Clinical Linguistics, Second Edition provides a timely and authoritative survey of this interdisciplinary field, exploring the application of linguistic theory and method to the study of speech and language disorders. Containing 42 in-depth chapters by an international panel of established and rising scholars, this classic volume addresses a wide range of pathologies while offering valuable insights into key theory and research, multilingual and cross-linguistics factors, analysis and assessment methods, and more. Now in its second edition, The ...
The Handbook of Bilingual and Multilingual Education
The Handbook of Bilingual and Multilingual Education presents the first comprehensive international reference work of the latest policies, practices, and theories related to the dynamic interdisciplinary field of bilingual and multilingual education. Represents the first comprehensive reference work that covers bilingual, multilingual, and multicultural educational policies and practices around the world Features contributions from 78 established and emerging international scholars Offers extensive coverage in sixteen chapters of language and education issues in specific and diverse regional/geographic contexts, including South Africa, Mexico, Latvia, Cambodia, Japan, and Texas Covers pedagogical issues such as language assessment as well as offering evolving perspectives on the needs of specific learner populations, such as ELLs, learners with language impairments, and bilingual education outside of the classroom
A half century of Romance linguistics: Selected proceedings of the 50th Linguistic Symposium on Romance Languages
The present volume presents a selection of the revised and peer-reviewed proceedings articles of the 50th Linguistic Symposium on Romance Languages (LSRL 50) which was hosted virtually by the faculty and students from the University of Texas at Austin. With contributions from rising and senior scholars from Europe and the Americas, the volume demonstrates the breadth of research in contemporary Romance linguistics with articles that apply corpus-based and laboratory methods, as well as theory, to explore the structure, use, and development of the Romance languages. The articles cover a wide range of fields including morphosyntax, semantics, language variation and change, sociophonetics, historical linguistics, language acquisition, and computational linguistics. In an introductory article, the editors document the sudden transition of LSRL 50 to a virtual format and acknowledge those who helped them to ensure the continuity of this annual scholarly meeting.
Joe Blackburn's a Clown's Log
Joseph Blackburn, a clown who juggled on horseback, took a professional trip to England in 1838, accompanied by the noted American vaulter and bareback rider, Levi J. North. His account of their experiences abroad encompasses activity with the circuses of
The Handbook of Discourse Analysis
The second edition of the highly successful Handbook ofDiscourse Analysis has been expanded and thoroughly updated toreflect the very latest research to have developed since theoriginal publication, including new theoretical paradigms and discourse-analytic models, in an authoritative two-volumeset. Twenty new chapters highlight emerging trends and the latestareas of research Contributions reflect the range, depth, and richness of currentresearch in the field Chapters are written by internationally-recognized leaders intheir respective fields, constituting a Who’s Who ofDiscourse Analysis A vital resource for scholars and students in discourse studiesas well as for researchers in related fields who seek authoritativeoverviews of discourse analytic issues, theories, and methods
The Handbook of Linguistics
"The first edition of this Handbook is built on surveys by well-known figures from around the world and around the intellectual world, reflecting several different theoretical predilections, balancing coverage of enduring questions and important recent work. Those strengths are now enhanced by adding new chapters and thoroughly revising almost all other chapters, partly to reflect ways in which the field has changed in the intervening twenty years, in some places radically. The result is a magnificent volume that can be used for many purposes." David W. Lightfoot, Georgetown University "The Handbook of Linguistics, Second Edition is a stupendous achievement. Aronoff and Rees-Miller have prov...
The Handbook of Language and Speech Disorders
An authoritative overview of language and speech disorders, featuring new and updated chapters written by leading specialists from across the field The Handbook of Speech and Language Disorders, Second Edition, provides timely and authoritative coverage of current issues, foundational principles, and new research directions within the study of communication disorders. Building upon the reputation of the landmark first edition, this volume offers an exceptionally broad and in-depth survey of the field, presenting original chapters by internationally recognized specialists that examine an array of language, speech, and cognitive disorders and discuss the most crucial aspects of this evolving d...
