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The electric field of the heart was described diagrammatically for the first time by A. Waller in 1888. However, it was not until a little more than ten years ago that with the development of micro electronic techniques, it became accessible to biophysical modeling, to exact physiological measurements, and to application in advanced clinical diagnosis. These possibilities opened the way to the treatment of questions which are called the direct and the inverse solution of the cardioelectric problem. Several groups of investigators are now working to achieve a complete biophysical and physiological description of the generation of the cardiac electric field. This work could well form the basis...
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This volume is in honour of Hermann von Helmholtz, one of the most famous founders of science in the nineteenth century who also stood at the gateway from classical to modern physics and philosophy. Emphasized is the role of inverse methodology in understanding the concept and theory of physical observation. The volume is concerned with strategies that deal with inference from experimentally observed data regarding the source generating the signal; that is with the logical inversion of cause and effect. The significance is shown of the need for an interpretation of the data which stems from the amount of theory involved in physical experiments. This problem was raised in an early work of Hel...