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In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort t...
One of the most time-consuming tasks in clinical medicine is seeking the opinions of specialist colleagues. There is a pressure not only to make referrals appropriate but also to summarize the case in the language of the specialist. This book explains basic physiologic and pathophysiologic mechanisms of cardiovascular disease in a straightforward manner, gives guidelines as to when referral is appropriate, and, uniquely, explains what the specialist is likely to do. It is ideal for any hospital doctor, generalist, or even senior medical student who may need a cardiology opinion, or for that ma.
Biography of Euan Ashley, currently co-Director, Clinical Genomics & Precision Medicine at Stanford Health Care, previously Founder and Advisor at Personalis, Inc. and Founder and Advisor at Personalis, Inc.
Chapter 8 Cardiovascular Screening for the Prevention of Sudden Cardiac Death in AthletesIntroduction; The Risk of Sudden Death in Athletes; Rationale for Screening Competitive Athletes; The Screening Programmes Implemented in Italy; Rationale for Including a 12-Lead ECG in the PPE ; Efficacy of Screening to Identify Cardiac Disease Risk; Impact of the Screening Programme on Cardiac Mortality; Costs of Systematic Screening across Italy; Limitations of Screening Programmes; Conclusion; References
This second edition of Genetics and Sports expands on topics previously discussed in an attempt to create an integrated and holistic understanding of the field of sports genomics. It is an update on technologies and on the role of genetics in training, performance, injury, and other exercise-related phenotypes. Ethical concerns and the importance of counselling before and after genetic testing are also addressed. It is increasingly important to understand the field of genetics and sports because of the potential to use and misuse information. All exercise scientists, sport and exercise clinicians, athletes, and coaches need to be adequately informed to ensure that genetic information is accurately and properly used. Genetics and Sports is, therefore, highly recommended to all of these groups.
The never-before-told story of Ewan Forbes and the landmark case that rocked British society and transformed transgender experience to this day'A remarkable story' The Times'Almost reads like a thriller' Sunday Times'One of the most important pieces of investigative journalism ever written about trans people' i-------------------Ewan Forbes was born Elisabeth Forbes to a wealthy landowning family in 1912. It quickly became clear that the gender applied to him at birth was not correct, and from the age of six he began to see specialists in Europe for help. With the financial means of procuring synthetic hormones, Ewan was able to live as a boy, and then as man, and was even able to correct th...
The racist legacy behind the Western idea of freedom The era of the Enlightenment, which gave rise to our modern conceptions of freedom and democracy, was also the height of the trans-Atlantic slave trade. America, a nation founded on the principle of liberty, is also a nation built on African slavery, Native American genocide, and systematic racial discrimination. White Freedom traces the complex relationship between freedom and race from the eighteenth century to today, revealing how being free has meant being white. Tyler Stovall explores the intertwined histories of racism and freedom in France and the United States, the two leading nations that have claimed liberty as the heart of their...
Written, reviewed, and edited in a collaborative effort by cardiology fellows and faculty of one of the most prestigious academic centers in the country, this concise volume gives cardiology fellows the book they have long needed. Keeping coverage of the underlying pathophysiology and mechanism of disease to a minimum, the authors focus on the diagnosis and treatment of cardiac disorders. Practical and easily accessible at the time of decision making, the book relays important concepts through concise and to-the-point pearls and by utilizing algorithm charts and illustrations.
A funny and intimate portrait of a relationship gleaned from the author and his fiance's couple's therapy sessions. Hilarious, thought-provoking, and compelling, "George & Hilly" reveals the uncensored, unselfconscious psyche of a man on the brink of matrimony.
In the last decade, genetics has been emerging as a primary issue in the diagnosis and management of cardiomyopathies. This book is intended to be a state-of-the-art monograph on these diseases, describing their genetic causes, defining the molecular basis and presenting extensive descriptions of genotype–phenotype correlations. Other chapters are focused on the role of clinical observation, on ECG and echocardiography. With its highlight on the most recent discoveries in the field of molecular genetics as well as on the correct clinical approach to patients with heart muscle disease, the book is aimed at physicians and clinical cardiologists with a particular interest in myocardial diseases and in their genetic causes.