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Parasite Genomics Protocols, Second Edition expands upon the previous edition with current, detailed methodologies that have been adapted to research parasites in the post genomic era. With new chapters on parasite studies, helminth pathogens, and protocols for undertaking other large-scale ‘omics’ methodologies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Parasite Genomics Protocols, Second Edition offers a wide-ranging collection of diverse methods and protocols for further study into these unique organisms.
Kaija Saariaho’s Emilie Suite was a joint commission by Carnegie Hall, New York City, Cité de la Musique, Paris, Luzerner Sinfonieorchester and Orchestre Philharmonique de Strasbourg. It was first performed on 30 November 2011 at Carnegie Hall by the Avanti! Chamber Orchestra conducted by Hannu Lintu, with Elizabeth Futral (soprano). The first performance in Paris took place on 23 April 2013 at Cité de la Musique by the Avanti! Chamber Orchestra conducted by Ernest Martinez Izquierdo, with Barbara Hannigan (soprano).
This accessible textbook offers balanced and uniformly excellent coverage of modern linguistics.
Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
Is your firm’s board creating value—or destroying it? Change is coming. Leadership at the top is being redefined as boards take a more active role in decisions that once belonged solely to the CEO. But for all the advantages of increased board engagement, it can create debilitating questions of authority and dangerous meddling in day-to-day operations. Directors need a new road map—for when to lead, when to partner, and when to stay out of the way. Boardroom veterans Ram Charan, Dennis Carey, and Michael Useem advocate this new governance model—a sharp departure from what has been demanded by governance activists, raters, and regulators—and reveal the emerging practices that are de...
It's a critical cliché that Cervantes' Don Quixote is the first modern novel, but this distinction raises two fundamental questions. First, how does one define a novel? And second, what is the relationship between this genre and understandings of modernity? In Forms of Modernity, Rachel Schmidt examines how seminal theorists and philosophers have wrestled with the status of Cervantes' masterpiece as an 'exemplary novel', in turn contributing to the emergence of key concepts within genre theory. Schmidt's discussion covers the views of well-known thinkers such as Friedrich Schlegel, José Ortega y Gasset, and Mikhail Bakhtin, but also the pivotal contributions of philosophers such as Hermann Cohen and Miguel de Unamuno. These theorists' examinations of Cervantes's fictional knight errant character point to an ever-shifting boundary between the real and the virtual. Drawing from both intellectual and literary history, Forms of Modernity richly explores the development of the categories and theories that we use today to analyze and understand novels.
Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.
Millions of believers are hungry for an uncompromising look at the roles of women in missions, ministry, and leadership. This book brings light, not just more heat, to the church's crucial debate through- historical and current global perspectives- a detailed study of women in Scripture- an examination of the fruit of women in public ministry- a powerful revelation of what's at stake for women, men, the body of Christ, God's kingdom, and the unreached
This book explores the work of Sir John Tenniel, the artist who illustrated the first editions of Lewis Carroll's best-known works. Although Tenniel and Carroll parted ways after publication of Through the Looking-Glass, the artist's designs fixed in the public's mind images of Carroll's characters that thrive down to the present day.