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Enzyme Induction
Our present concepts ofthe regulation of enzyme activity in the cell have been largely based on the extensive body of work which has been carried out with micro-organisms. A distinction between constitutive and adaptive enzymes had already been made well before World War II and work on enzyme adaptation, both in yeast and bacteria, was done by several workers, especially Marjorie Stephenson and her group in Cambridge in the 1930s. In studies starting about 1947 Stanier demonstrated that the oxidation of aromatic compounds by species of Pseudomonas involved the coordinate and sequential induction of a group of enzymes concerned in the orderly catabolism of a substrate which acted as the induc...
The Porphyrin Handbook
The Porphyrin Handbook, Volume 14: Medical Aspects of Porphyrins provides information pertinent to every aspect of the chemistry, synthesis, spectroscopy, and structure of phthalocyanines. This book examines the biology and medical implications of porphyrin systems. Organized into 12 chapters, this volume begins with an overview of the underlying diagnostic features, mechanisms, and available treatments of erythropoietic disorders due to defective heme biosynthesis. This text then examines the physiopathology of acute intermittent porphyria, which is transmitted as autosomal dominant disorders with incomplete penetrance. Other chapters consider the main characteristics of congenital erythropoietic porphyria, which includes an increased synthesis, accumulation, ad excretion of porphyrins. This book discusses as well the biochemistry, pathophysiology, and clinical features of variegate porphyria in the light of several essential advances in the understanding, management, and diagnosis of variegate porphyria. The final chapter deals with the legal use of herbal and complementary medicines. This book is a valuable resource for research scientists, engineers, and clinicians.
Biological Reactive Intermediates
The concept that detoxication is the inevitable result of biotransformation of xenobiotic compounds by mammalian systems has undergone modification since it was first described. Indeed, despite the fact that R. T. Williams popularized the notion, he was among the first to caution that it was not possible to predict the biological activities of the resulting metabolites. It has become increasingly apparent in recent years that not only do many metabolites of drugs and other chemicals display biological activity but also in many instances these metabolites play an important role in initiating several forms of cancer and are the cause of a variety of types of toxicity. Thus it seems appropriate...
Toxicology and Experimental Models
Advances in Pharmacology and Therapeutics II, Volume 5: Toxicology and Experimental Models is the fifth of a six-volume compilation of the scientific papers of invited speakers of the Eighth International Congress of Pharmacology. Organized into six parts, this book begins by elucidating the rational interpretation of species and strain differences in toxicity for the prediction of risk to man. Subsequent parts discuss the chemical interactions resulting in liver and kidney injury; the role of heme synthesis and degradation in predicting drug toxicity; and delayed toxic effects of pre- and perinatal drug exposure. Other chapters describe models of experimental peptic ulcers and therapeutic agents and models and quality control of laboratory animals.
Photonics and Photoactive Materials
The book focuses on innovative photonic and photoactive materials and such topics as photonic structures, silicon photonics, nanomaterials, plasmonics, graphene quantum dots, optically active defects, fluorescent materials and optical sensors. The generation of light, absorption, emission, transmission, optical sensing and probing, signal processing and data transmission are some of the properties related to this growing field. Keywords: Photonic Structures, Silicon Photonics, Plasmonics, Silver Nanoparticles, Graphene Quantum Dots, Optically Active Defects, Fluorescent Materials, Optical Sensors, Fullerene, Proton Beam Detectors, Lithium Fluoride Films, Signal Processing, Data Transmission.
Hepatotoxicology
This book is destined to serve as a classic reference source to which researchers can turn for a historical perspective and basic information on the physiology, biochemistry, and pathology of the liver. Major areas covered in the book include histological organization, classification of chemical-induced injury, stages of cellular injury, and xenobiotic metabolism. Chapters discussing the use of biochemical methods to determine liver damage, the effects of various chemical agents of the liver, and hepatocarcinogenesis are also presented. Toxicologists, physiologists, physicians, biochemists, industrial hygienists, and others interested in the effects of chemical agents on the structure and function will find this book to be an indispensable source of information.
Current List of Medical Literature
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
Biochemical and Clinical Aspects of Oxygen
Biochemical and Clinical Aspects of Oxygen contains the proceedings of a symposium held on the Pingree Park Campus of Colorado State University on September 24-29, 1978. Contributors discuss the biochemical and clinical aspects of oxygen, focusing on reactions and areas relating to heme, flavin, copper and nonheme iron proteins, organ transplants, carbon monoxide formation and detoxification, oxidant drugs and pollutants, oxygen toxicity, enzyme inactivation, lipid peroxidation, membrane destruction, antioxidants, cataractogenesis, mutagen and carcinogen formation, malaria and trypanosome parasites, and inflammation. This volume is organized into 51 chapters and begins with a discussion of b...
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
