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B-Endorphin
Hormonal Proteins and Peptides: ß-Endorphin, Volume X focuses on the chemistry, biology, and clinical investigations of opioid peptides. This book discusses the chemical approach in isolating a chemical entity from its natural source and investigates its biological activity after it has been determined to be a pure substance. Organized into nine chapters, this volume starts with an overview of the structure–activity relationship of ß-endorphin (ß-EP) by synthetic approach. This text then explores the proteinases involved in the generation of opioid peptides, including ß-EP from ß-lipotropin (ß-LPH). Other chapters review the biosynthesis of ß-EP and consider in detail the opiate receptor. This book discusses as well the anatomy of ß-EP-containing structures in pituitary and brain. The final chapter presents a discussion on the historical aspects of opiate–peptide discoveries, particularly in the field of narcotic antagonists. This book is a valuable resource for chemists, biologists, endocrinologists, physicians, and neurobiologists.
Central Analgetics
An up-to-date review of the physiology, pharmacology, and chemistry used to develop drugs to treat pain. Experts cover such topics as the neural pathways involved in pain sensation; traditional and new test systems for potential analgetic agents; current research on oligopeptide enkephalins; and the organic and medicinal chemistry of central analgetics.
Psychopharmacogenetics
This book addresses the basic and advanced knowledge on psychiatric disorders for non-clinicians. The volume compiles in-depth information on the psychopharmacogenetic, representing an important area of research that is based on various specialties including clinical psychiatry, pharmacology, neurobiology and genetics. The book also addresses questions related to the field of psychiatric disorders that are not usually addressed in one work. The questions considered include: What is schizophrenia? What are the risk factors? What are the core symptoms? How is it treated? What are the efficacy and side effects of the available treatments?
Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry
Drug Addiction I
This volume addresses the general problem of drug addiction from several points of view, which are in some ways quite unique and different from other areas of pharmacology. Drug addiction is closely associated with criminal behavior. One of the great and noble edifices of civilization is the philosophic and ethical view that man is perfectible, and some believe that this can be achieved by providing the appropriate circumstance or environment in which man can mature and be educated. Some have postulated that drug abuse is a consequence of an inadequate or pathologic set of socializing experiences or is a consequence of basic conflicts between the values and accepted patterns of behavior of a...
